ID   A0A3B5Y4L5_WHEAT        Unreviewed;       616 AA.
AC   A0A3B5Y4L5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G347700.3};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G347700.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS1A02G347700.3};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G347700.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B5Y4L5; -.
DR   EnsemblPlants; TraesCS1A02G347700.3; TraesCS1A02G347700.3; TraesCS1A02G347700.
DR   Gramene; TraesCS1A02G347700.3; TraesCS1A02G347700.3; TraesCS1A02G347700.
DR   Gramene; TraesCS1A03G0853300.3; TraesCS1A03G0853300.3.CDS; TraesCS1A03G0853300.
DR   Proteomes; UP000019116; Chromosome 1A.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050664; F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor; IEA:InterPro.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR   InterPro; IPR013623; NADPH_Ox.
DR   PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR   PANTHER; PTHR11972:SF202; OS05G0528000 PROTEIN; 1.
DR   Pfam; PF01794; Ferric_reduct; 1.
DR   Pfam; PF08414; NADPH_Ox; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        400..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        539..559
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        579..602
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          276..311
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          1..112
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   616 AA;  68779 MW;  94C24CFBE157C896 CRC64;
     MRGVGGGGGL GAPGRARWGG SGATTPRSLS TGSSPRGSDR SSDDGEELVE VTLDLQEDDT
     IVLRSVEPAA AANASANASS GASPSVMGWG AEPTPPPGAG AGPSRSRSPA IRRTSSHRLL
     QFSQELKAGV SRAKQISQDL TKRFTRTQSR AALAEPPAHP PSGIESALAA RAERRQRAQL
     DRTKSTAQRA IKGLRFISGN AKASNNAWIE VQRNFDRLAL DGRLSRADFP QCIGMMESKE
     FAMELFDTLC RRRQMQSDHI NREELREIWS QITDNSFDSR LQIFFDMVDK DADGHITEAE
     VKEIIMLSAS ANKLARLKEQ AEEYAALIME ELDPEGLGYI ELWQLETLLL QKDTYVNYSQ
     ALSYTSQALS QNLAGLRHKS PIRKMSSKLS YYLEDNWKRL WVLALWIGIM VGLFIWKFIQ
     YRNRYVFSVM GYCVTIAKGA AETLKLNMAL ILLPVCRNTI TWLRNTRAAR ALPFDDNINF
     HKTIAAAIVV GVILHAGNHL ACDFPRLIDS SDETYGPLRK YFGETKPTYL ALVRGVEGVT
     GVIMVVCMLI AFTLATRWFR RSLVKLPKPF DKLTGFNAFW YSHHLFIIVY ISLVIHGERL
     YLILDWYKRT SLLGYM
//