ID A0A3B5Y5T3_WHEAT Unreviewed; 222 AA.
AC A0A3B5Y5T3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Calcineurin B-like protein {ECO:0000256|RuleBase:RU369080};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1A02G352200.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS1A02G352200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1A02G352200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1A02G352200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- FUNCTION: Acts as a calcium sensor. CBL proteins interact with CIPK
CC serine-threonine protein kinases. Binding of a CBL protein to the
CC regulatory NAF domain of a CIPK protein lead to the activation of the
CC kinase in a calcium-dependent manner. {ECO:0000256|RuleBase:RU369080}.
CC -!- SUBUNIT: Homodimer. Interacts with CIPK.
CC {ECO:0000256|RuleBase:RU369080}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU369080}.
CC -!- SIMILARITY: Belongs to the calcineurin regulatory subunit family.
CC {ECO:0000256|ARBA:ARBA00023774, ECO:0000256|RuleBase:RU369080}.
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DR AlphaFoldDB; A0A3B5Y5T3; -.
DR SMR; A0A3B5Y5T3; -.
DR STRING; 4565.A0A3B5Y5T3; -.
DR PaxDb; 4565-Traes_1AL_021B94DEB-1; -.
DR EnsemblPlants; TraesCS1A02G352200.1; TraesCS1A02G352200.1; TraesCS1A02G352200.
DR Gramene; TraesCAD_scaffold_029136_01G000100.1; TraesCAD_scaffold_029136_01G000100.1; TraesCAD_scaffold_029136_01G000100.
DR Gramene; TraesCLE_scaffold_034548_01G000800.1; TraesCLE_scaffold_034548_01G000800.1; TraesCLE_scaffold_034548_01G000800.
DR Gramene; TraesCS1A02G352200.1; TraesCS1A02G352200.1; TraesCS1A02G352200.
DR Gramene; TraesCS1A03G0864200.1; TraesCS1A03G0864200.1.CDS; TraesCS1A03G0864200.
DR Gramene; TraesKAR1A01G0338380.1; cds.TraesKAR1A01G0338380.1; TraesKAR1A01G0338380.
DR Gramene; TraesPAR_scaffold_042947_01G000100.1; TraesPAR_scaffold_042947_01G000100.1; TraesPAR_scaffold_042947_01G000100.
DR Gramene; TraesROB_scaffold_034221_01G000900.1; TraesROB_scaffold_034221_01G000900.1; TraesROB_scaffold_034221_01G000900.
DR Gramene; TraesWEE_scaffold_030606_01G000100.1; TraesWEE_scaffold_030606_01G000100.1; TraesWEE_scaffold_030606_01G000100.
DR OMA; PPGFENH; -.
DR OrthoDB; 90710at2759; -.
DR Proteomes; UP000019116; Chromosome 1A.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0019900; F:kinase binding; IEA:UniProtKB-UniRule.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:UniProtKB-UniRule.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR045198; CNBL1-10.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23056; CALCINEURIN B; 1.
DR PANTHER; PTHR23056:SF143; CALCINEURIN B-LIKE PROTEIN 8; 1.
DR Pfam; PF13202; EF-hand_5; 2.
DR PRINTS; PR00450; RECOVERIN.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|RuleBase:RU369080};
KW Membrane {ECO:0000256|RuleBase:RU369080};
KW Metal-binding {ECO:0000256|RuleBase:RU369080};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU369080}.
FT DOMAIN 73..108
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 110..145
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 154..189
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 222 AA; 25284 MW; 5DAE8CBE0B0A8D05 CRC64;
MGCAFSSSPS PRKREQRAQG YEEPAVLAAE TSFTVNEVEA LYELYKKLSF SIFKDGLIHK
EEFRLALFRT SRGANLFADR VFDLFDLKRN GVIEFGEFVR SLSIFHPKAP ESEKTAFAFK
LYDLRGTGYI EKEELREMVV ALLDESDLCL SDSAVEEIVH NTFSQADSDG DGRIDPKEWE
EFVKQNPASL RNMSLPYLQD ITTTFPSFVM HSEVEDYSGI SK
//
