ID A0A3B5YR98_WHEAT Unreviewed; 419 AA.
AC A0A3B5YR98;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_004823 {ECO:0000313|EMBL:KAF6987154.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1B02G020900.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF6987154.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6987154.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1B02G020900.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G020900.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1B02G020900.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6987154.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6987154.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022212; KAF6987154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5YR98; -.
DR SMR; A0A3B5YR98; -.
DR PaxDb; 4565-Traes_1BS_0F00F3F9A-1; -.
DR EnsemblPlants; TraesCS1B02G020900.1; TraesCS1B02G020900.1.cds1; TraesCS1B02G020900.
DR Gramene; TraesCS1B02G020900.1; TraesCS1B02G020900.1.cds1; TraesCS1B02G020900.
DR Gramene; TraesCS1B03G0042000.1; TraesCS1B03G0042000.1.CDS1; TraesCS1B03G0042000.
DR OMA; TFTEWEN; -.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF931; OS01G0547000 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 1..54
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 120..349
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 65..92
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 419 AA; 47913 MW; A532E2004A2A3CC9 CRC64;
MQAYLQEAEQ FKDTDKTTAI FIGKIRGLAF QIEDVVDEFN YKLEDCKHGR FTGKMKKRLK
HIKTWRRLAA KLQEIEAQLQ DANRRKKDYA VTGRSASAAR STREGQALHF TRDEDLVRIE
EHKEGLIQWL NGGGDDPERS SSKVTMVWGM PGVGKTTLVD HVYNTVKADF DGAACVTVSG
SYRIENLLKK IAAQFNITVD VTTVEMRGLA KSILNYLQGK KYILILDGVW DEHLWSEIRD
VFPTSNCTGR FVITSRKQVV LATRESAYAI HLELLQEHYS WLLFTNEAFG NADDKECPLE
LQELARKFIA KCQGLPISIR CIGRLLSLKP PISAEWEDVY RGLDLQMAKD VIPDAHMILK
VSLEALPYNL KNCFIHCALF PDDYVLKRMK MIRQWIAAGF IWEKDDSKTL EEVPEGYLV
//
