ID A0A3B5YTL6_WHEAT Unreviewed; 874 AA.
AC A0A3B5YTL6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=E3 SUMO-protein ligase SIZ1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_005473 {ECO:0000313|EMBL:KAF6987876.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1B02G083900.5};
RN [1] {ECO:0000313|EMBL:KAF6987876.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6987876.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1B02G083900.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G083900.5};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1B02G083900.5}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6987876.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6987876.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the PIAS family.
CC {ECO:0000256|ARBA:ARBA00005383}.
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DR EMBL; CM022212; KAF6987876.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5YTL6; -.
DR SMR; A0A3B5YTL6; -.
DR STRING; 4565.A0A3B5YTL6; -.
DR EnsemblPlants; TraesCS1B02G083900.5; TraesCS1B02G083900.5; TraesCS1B02G083900.
DR Gramene; TraesCS1B02G083900.5; TraesCS1B02G083900.5; TraesCS1B02G083900.
DR Gramene; TraesCS1B03G0213800.6; TraesCS1B03G0213800.6.CDS; TraesCS1B03G0213800.
DR Gramene; TraesKAR1B01G0055070.2; cds.TraesKAR1B01G0055070.2; TraesKAR1B01G0055070.
DR OrthoDB; 921278at2759; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR GO; GO:0061665; F:SUMO ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IBA:GO_Central.
DR CDD; cd15570; PHD_Bye1p_SIZ1_like; 1.
DR CDD; cd16792; SP-RING_Siz-like; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR InterPro; IPR031141; SIZ1/2_SP-RING.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10782:SF4; E3 SUMO-PROTEIN LIGASE SIZ1; 1.
DR PANTHER; PTHR10782; ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02037; SAP; 1.
DR Pfam; PF02891; zf-MIZ; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 12..46
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT DOMAIN 353..434
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
FT REGION 86..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 874 AA; 97079 MW; 9B818E8A4498C649 CRC64;
MADLASTCKD KLAYFRIKEL KDILHQLGLP KQGKKQDLID RVLALLSDEQ GQRHHGWGRK
NSFTKEAVAK IVDDIYSRKM QIQSAPDLAT RSHTGSDLFR PKDEVNDSFQ PQPVTKVRCI
CDSKLLNDNM IQCEDDRCHV WQHMSCVLVP DKPTEGVGPE VPPHFYCELC RLSRADPFWV
TTGNPLPPLK FMSSGVANDG TSVLQTVEKT FQLSRADRET VQRSEYDLQV WCILMNDKVQ
FRMQWPQYAE LEVNGFAVRV VTRPGSQLLG INGRDDGPLI TTCSREGTNK ICLRRVDNRT
FCFGVRVARR RSVPQVLNLV PKEAEGESFE DALTRVRRCL GGGDTAENAD SDSDLEVVTE
SVTVNLRCPN SGSRMKTAGR FKPCVHMGCF DLDTFVELNQ RSRKWQCPIC LKNYSLENLM
IDPYFNRITS LLRDCSEDVN EIDIKPDGSW RIKGDVPTRE LSQWHMPDGT LCILKEDNKP
GVENFNELKI EGTSDGHKSL KIGIKRKNGI WEVSNKADDK KPSVVGNITQ NNITFRTPNT
FPMSSSPTGS YRDGEDTSVN QEGSMHIDLS LNNGHEFESF PLNFGQTYNT EDTSQQQLSA
GDVIVLSDSD EENDTIVCPP TVYDNSTVND GGFPFATSDA GFTGRYQEDP GVGTSGLGLL
SNNADDFEMT NWQMPYSQPE QGYQFFGDGT ADTYVGSHNS FSITPNDYSL DCNVGIEEAS
VAHDLPVYRS NNEMHGSLVD NPLAFGGDDP SLQIFLPSQP SSAPLQEEPS ERVNASNGVQ
SDDWISLTLA AGGGGNEVPA AANGLNLQEQ IRSNETGVEP LIDAASVLPS TNNDRDDGAN
LNPIRIENIF SHPRQPRSRS VRPRLCLSID SDSE
//
