ID A0A3B5YV92_WHEAT Unreviewed; 911 AA.
AC A0A3B5YV92;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=HRDC domain-containing protein {ECO:0000259|PROSITE:PS50967};
GN ORFNames=CFC21_006251 {ECO:0000313|EMBL:KAF6988800.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1B02G155600.1};
RN [1] {ECO:0000313|EMBL:KAF6988800.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6988800.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1B02G155600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G155600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1B02G155600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6988800.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6988800.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022212; KAF6988800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5YV92; -.
DR SMR; A0A3B5YV92; -.
DR STRING; 4565.A0A3B5YV92; -.
DR EnsemblPlants; TraesCS1B02G155600.1; TraesCS1B02G155600.1; TraesCS1B02G155600.
DR Gramene; TraesCAD_scaffold_060862_01G000200.1; TraesCAD_scaffold_060862_01G000200.1; TraesCAD_scaffold_060862_01G000200.
DR Gramene; TraesCLE_scaffold_051077_01G000200.1; TraesCLE_scaffold_051077_01G000200.1; TraesCLE_scaffold_051077_01G000200.
DR Gramene; TraesCS1B02G155600.1; TraesCS1B02G155600.1; TraesCS1B02G155600.
DR Gramene; TraesCS1B03G0450000.2; TraesCS1B03G0450000.2.CDS; TraesCS1B03G0450000.
DR Gramene; TraesPAR_scaffold_057275_01G000100.1; TraesPAR_scaffold_057275_01G000100.1; TraesPAR_scaffold_057275_01G000100.
DR Gramene; TraesRN1B0100454300.2; TraesRN1B0100454300.2; TraesRN1B0100454300.
DR Gramene; TraesROB_scaffold_065951_01G000100.1; TraesROB_scaffold_065951_01G000100.1; TraesROB_scaffold_065951_01G000100.
DR Gramene; TraesWEE_scaffold_066554_01G000100.1; TraesWEE_scaffold_066554_01G000100.1; TraesWEE_scaffold_066554_01G000100.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IBA:GO_Central.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0071044; P:histone mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071040; P:nuclear polyadenylation-dependent antisense transcript catabolic process; IBA:GO_Central.
DR GO; GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IBA:GO_Central.
DR GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071036; P:nuclear polyadenylation-dependent snoRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071037; P:nuclear polyadenylation-dependent snRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IBA:GO_Central.
DR GO; GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IBA:GO_Central.
DR CDD; cd06147; Rrp6p_like_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR045092; Rrp6-like.
DR InterPro; IPR049559; Rrp6p-like_exo.
DR PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR PANTHER; PTHR12124:SF73; PROTEIN RRP6-LIKE 2; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 478..558
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..893
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..911
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 911 AA; 100628 MW; 051BE45DAED0B347 CRC64;
MEADEAPHPP PPWKQNKSAV AVDASSGPLA SAAARLSARS RAIPPARDFH FYNNFPSFKS
PVAAAAARAE SSLAVLGASM LLPKQQQQPF PTEDLDDAYD WLVARNDDLL EMFAASADEF
KALREKEEAQ GRKVAAEEMA GDGFQVVYGK KKKKMGMGEE GVGRSEAFGS SGSVRMATMD
RAAASGPKPK VPFHIPTIPR PQDVHRIVVD NTSKPFDHAF LERSDDGARA IHPLEKLPME
QLFDRRVPES EPLKPPALDD TPFTFVEDRK TLEVLVAKLK SATEFAVDLE HNHYRSFQGL
TCLMQISTRT EDFIVDTLKL RNCLGENLRE VFQDPTKKKV MHGAGRDIIW LQRDFGIYVC
NLFDTGQASR ILQMDRNSLE HLLQYFCGVT ANKEYQSADW RLRPLPDEMT KYAREDTHYL
LYIYDLMRLR LVNESSGDDL LLEVCKRSNE ICLQLYEKEL LTDSSYLYIH GLKENDLSAR
QLAVLAGLYQ WRDGVARAED ESTGYILPNK TLLEIAKQMP VTTGRLKRTV KSKNKFLEHY
LGHVITIIRN AVANADAFES IAEQLKKGRL EEVVLLMAAE AKDGSEDTEM IPAVDADSNE
NNLQLIAAPD VAPTVITNVH TASFCMGNVT SGASLGNLQL DNITPETKSF GALPGATEQA
DTVIPGNGGG QQQVIKATVQ VSKRPTAFGA LLGKPSTARR PNLFPGFSSD QSKSKVEKIK
SSVVLPFHHF SGGANPPASS LPVAKSVEPE AEIMCEDPAS RMEEVIQLDT GTDDPENGNA
DGQSECKPGD TDVCSSPPEL SSGIEQRFRS LNESRDLQQK HQALEEPEFN DQLKAFDYAE
ARKNTSFGEV RSERRKDNAV ARAINADSGD KRKSSKQTPD AGGGEEDEGN FQNPRRRQAF
PPSGNRSDTY H
//
