ID A0A3B5YW88_WHEAT Unreviewed; 1497 AA.
AC A0A3B5YW88;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ATP-dependent helicase ATRX {ECO:0000256|ARBA:ARBA00031106};
GN ORFNames=CFC21_006315 {ECO:0000313|EMBL:KAF6988884.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1B02G161400.2};
RN [1] {ECO:0000313|EMBL:KAF6988884.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6988884.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1B02G161400.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G161400.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1B02G161400.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6988884.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6988884.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, telomere
CC {ECO:0000256|ARBA:ARBA00004574}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM022212; KAF6988884.1; -; Genomic_DNA.
DR EnsemblPlants; TraesCS1B02G161400.2; TraesCS1B02G161400.2; TraesCS1B02G161400.
DR Gramene; TraesCS1B02G161400.2; TraesCS1B02G161400.2; TraesCS1B02G161400.
DR Gramene; TraesCS1B03G0468900.2; TraesCS1B03G0468900.2.CDS; TraesCS1B03G0468900.
DR OMA; FFAKCQI; -.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd11726; ADDz_ATRX; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR025766; ADD.
DR InterPro; IPR044574; ARIP4-like.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45797:SF1; HELICASE ARIP4; 1.
DR PANTHER; PTHR45797; RAD54-LIKE; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51533; ADD; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Telomere {ECO:0000256|ARBA:ARBA00022895};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 504..635
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51533"
FT DOMAIN 761..944
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1146..1317
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 52..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1402..1457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 113..147
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 52..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1415..1429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1432..1457
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1497 AA; 169371 MW; B6C57FE6E77EFC70 CRC64;
MDVNGKLSDG DLKKTEALHS NGQPVDDVII IESEGDENKV VVETNIIEGP FEEHKEHRCG
KTDNSVHEEA STSTDDGSDS DLYGFLRESE NEQTSESDVE ETDIEVALPE EKVEELIAEF
HDVESKAAEA QESLEKESLE KIEAEVRLEL SERLQGDALD LAVSIEMEQF KKEWSSELDD
LEIRSAVLLE ELDAAGVELP SLYKSIESQA PNVCETEAWK NRTHWAGSQV PEQANQSIRK
ADEYLQSCRP VRRKHGRLLE EGASGFLAGK VPVVDDDSVQ CHEKSWSSFN ELIKSSECAK
TSFGSSNWAS VYLANTPQEA AALGLQFPGV DEVEEIAEVD GAVDDIKCVD EIELSEEQRR
KYRKVREEDD AKAIKRLRRY MEKRTDGWCK VTAHGNIGLA SSSNGCCKLP LDDGVLDANS
GCPESEKQKM GKDEVSAELL KRTREDDVEL DHKRSKTVVI ESDDDMLMDS KLVLHIKDSK
RSSAELEKGV DIIDLDLFPS QSPKFSDMDL PKSFKCTICT KMLNASDVHR HPVLDVAVCG
SCRFLVIEKN RLEGPVSGGY CTWCVQCEQL LSCSSCKMLF CTKCLLKNLG EKCISEAKVT
GWQCCCCQPS QLEHLISECD KALSGVESSD LEGDNTSGTE TNDPVSKHKR KKKIRRIMDD
TELGEETKRK IAMEKARQEH LKSMHEQSAS KLRSSNIGTS SGALSEVFLQ DAGDGHIVNP
AREEDEEPVR IPSSISAKLK PHQVAGIIFM WENVIQSVRT VKSGDKGFGC ILAHNMGLGK
TFQVITFLYV VMRCAQLGLR TALIVTPVNV LHNWKKEFTK WQPAELKPLR VYMLEDVPRL
KRLYLLNKWR AKGGVLLIGY SSFRNLSLGR HVKEKDTADE ISNALQCGPD ILVCDEAHMI
KNRKADTTHA LKQVKTQRRI ALTGSPLQNN LMEYYCMVDF VREGFLGSSH EFRNRFQNPI
ENGQHTNSTS DDVKIMNQRS HILYEQLKGF VQRMDMNVVK NDLPPKKVFV ITVKLSQLQR
KLYRRFLDVH GFSSGTSEKP YQHGGFFAKY QKLALIWNHP GLLQMAKEQR GSLRREDAVE
NFLTDESSSD DNHNIEIQLP NGGKQKSRTD QQSKKIDFWD EESNWWDNLL DDNTFKEADY
SGKMVLLLDI LATCYELGDK ALVFSQNLTT LDLVEFYLSK MQIKGKEGKY WKQGKDWYRL
DGSTPSSERQ NLVERFNDPA NTKVKCTLIS TRAGSLGINL HAANRVVLLD GSWNPTHDLQ
AIYRVWRYGQ MKPVYAYRLM AHGTMEEKIY KRQVTKEGLA ARVVDRQQVS RTISKEEMLH
LFEFGDEEML DESGNDTIID HSKVGTEKLS MPNSTELPVD TLMQNLLSDH PRWIAGYHEH
EVLLQENEEE RLTKEEQDMA WSNFKQSQQL DAVARKGAHD SERKPIETNP RPPKVTSRSR
QAQQPKSHSN NQKKCTNLNH MLTLRSHGTK AGCTTSCDEC GQNISWETLN RSDGRLR
//
