ID A0A3B5Z1X7_WHEAT Unreviewed; 769 AA.
AC A0A3B5Z1X7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_007876 {ECO:0000313|EMBL:KAF6990710.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1B02G315300.1};
RN [1] {ECO:0000313|EMBL:KAF6990710.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6990710.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1B02G315300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1B02G315300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1B02G315300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6990710.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6990710.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022212; KAF6990710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5Z1X7; -.
DR STRING; 4565.A0A3B5Z1X7; -.
DR EnsemblPlants; TraesCS1B02G315300.1; TraesCS1B02G315300.1; TraesCS1B02G315300.
DR Gramene; TraesCS1B02G315300.1; TraesCS1B02G315300.1; TraesCS1B02G315300.
DR Gramene; TraesCS1B03G0865300.1; TraesCS1B03G0865300.1.CDS; TraesCS1B03G0865300.
DR Gramene; TraesPAR_scaffold_018386_01G000100.1; TraesPAR_scaffold_018386_01G000100.1; TraesPAR_scaffold_018386_01G000100.
DR Gramene; TraesROB_scaffold_020649_01G000100.1; TraesROB_scaffold_020649_01G000100.1; TraesROB_scaffold_020649_01G000100.
DR Gramene; TraesWEE_scaffold_016262_01G000100.1; TraesWEE_scaffold_016262_01G000100.1; TraesWEE_scaffold_016262_01G000100.
DR Proteomes; UP000019116; Chromosome 1B.
DR Proteomes; UP000815260; Chromosome 1B.
DR GO; GO:0070531; C:BRCA1-A complex; IBA:GO_Central.
DR GO; GO:0031436; C:BRCA1-BARD1 complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IBA:GO_Central.
DR GO; GO:0035067; P:negative regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0035066; P:positive regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR PANTHER; PTHR13763:SF8; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00292; BRCT; 2.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 156..277
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 532..604
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 83948 MW; B3F7D1A63268CD03 CRC64;
MGSGSGAVVW REILASSPPP GFGRPTGGLG ATASGSQRPS PAPGFGAARP SSTQSGGTKS
ATRTDMLVDI GTEAGCDNLE VPRHVGNGSA SPAKGTKRKF VVDATKGASP GVNASNTGQH
LHSRRKGKGP GKHAKLEDNK GATRLGRDQT PIGVFEDECV FCHSFRTSEQ FHGPMVLYHN
RRIVPSDEGI PTNAIYVHEK CMVWAPKVES NGDTFKNVES EINRSKRLRC RRCKLRGAAL
GCIDNSCRKS YHVPCAMMIP ECRWDDENRR VWCPKHAPPD QMSSPTMESD TLSPVLQNHS
SQCPAKEVSV DFQMEDERIN PLPCDEMSSQ IIESDITSAV LQSHSSQCPT KEISVNCQME
DEHINPLPGD EMSSPIIETD ITSAVLQNHS SQCPAKEISV DCQMEDEHIN PLPGDEMSSP
IIETDITSAV LQNHSSQCPA KEISSDCQME NEHINPLATS NSSLPGHVPG QYLVKGGTSV
LHRREDLQVD QLNTLSSSLP QGLCSDRGRI SANHRREEKL VNQSSTPVDQ WVLLGIPLSA
SEKDSLKEFA SLTSSTLAEE WDKNVTHVIV GRNAGDACGR SYEVLMAILS GKWVVTAGWI
VDCLVEPIPD LKTCLEKPIP GPEISYEMNF CDGSCTSGYG PMKGRARAAE RAPKLFSGLH
FCLSAYIDPE DRETIQRLVA AGEGQVLEGI SPDRLHENLN RNPAEVYFIY DSGPPRKITS
DFDLILGKEI QESVEYAKSG AQVISHRRLL DAILCYDARI LERRPHQDM
//
