ID A0A3B5ZY29_WHEAT Unreviewed; 523 AA.
AC A0A3B5ZY29;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_012789 {ECO:0000313|EMBL:KAF6996453.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1D02G304000.1};
RN [1] {ECO:0000313|EMBL:KAF6996453.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6996453.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1D02G304000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1D02G304000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1D02G304000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6996453.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6996453.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022213; KAF6996453.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5ZY29; -.
DR SMR; A0A3B5ZY29; -.
DR STRING; 4565.A0A3B5ZY29; -.
DR EnsemblPlants; TraesCS1D02G304000.1; TraesCS1D02G304000.1; TraesCS1D02G304000.
DR Gramene; TraesCAD_scaffold_048158_01G000100.1; TraesCAD_scaffold_048158_01G000100.1; TraesCAD_scaffold_048158_01G000100.
DR Gramene; TraesCLE_scaffold_137806_01G000100.1; TraesCLE_scaffold_137806_01G000100.1; TraesCLE_scaffold_137806_01G000100.
DR Gramene; TraesCS1D02G304000.1; TraesCS1D02G304000.1; TraesCS1D02G304000.
DR Gramene; TraesCS1D03G0725700.1; TraesCS1D03G0725700.1.CDS; TraesCS1D03G0725700.
DR Gramene; TraesPAR_scaffold_132622_01G000100.1; TraesPAR_scaffold_132622_01G000100.1; TraesPAR_scaffold_132622_01G000100.
DR Gramene; TraesROB_scaffold_075012_01G000400.1; TraesROB_scaffold_075012_01G000400.1; TraesROB_scaffold_075012_01G000400.
DR Gramene; TraesWEE_scaffold_029315_01G000100.1; TraesWEE_scaffold_029315_01G000100.1; TraesWEE_scaffold_029315_01G000100.
DR OMA; PRYMEGL; -.
DR Proteomes; UP000019116; Chromosome 1D.
DR Proteomes; UP000815260; Chromosome 1D.
DR GO; GO:0070531; C:BRCA1-A complex; IBA:GO_Central.
DR GO; GO:0031436; C:BRCA1-BARD1 complex; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IBA:GO_Central.
DR GO; GO:0035067; P:negative regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0035066; P:positive regulation of histone acetylation; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 3.40.50.10190; BRCT domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR PANTHER; PTHR13763:SF8; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00292; BRCT; 2.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 105..217
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 268..363
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 58147 MW; 6D056CAC40A9FF9E CRC64;
MLAESESKDD VPCSWSTTND NEAGPSHFPG VITMCSSNLG LDDDFEGASS GVNASNTGQQ
LPSCRKGKGP GKHAKLKGND GATGLGRVQT PVGVFEDECI FCHSFRTSEP CHGPMVLYHD
RRIMPNDKGN PTNAVYVHEK CIVWAPRVQS SGSTFKNVEN EINRASRWEC SRCNLRGAAL
GCYYGHCRKT YHVACAMMIP ECRWDVEGLH VWCPNHAPHD DMSSPTMESD IVLQVDQLNT
SSSSLSQGQC SDKERISSNY RREQNLQNQS STLVDQWVLL GISLSASEED SLKEFASLTN
STLVEDWDKN VTHVIVGRNT DTACVRSYAV LMAILYGKWI VRAGWIVDFL VQRIPHPETP
YEMTFYGGLH TSISGPTKGR ARAAEGDYNL LARDPRYMEG LSEAPKLFSG LNFCFSAYLH
VEDLEDFQNL IAAGGGQPME GVSPDSLPEI RNRFPGKVYF IYHGGPPRDS TRYFNCILKK
QIEECVEYGK SGAQVISHLM LYDAILSYDA RILEPGRSFH EYM
//
