ID A0A3B5ZZ93_WHEAT Unreviewed; 345 AA.
AC A0A3B5ZZ93;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DUF4220 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_013299 {ECO:0000313|EMBL:KAF6997038.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1D02G355900.1};
RN [1] {ECO:0000313|EMBL:KAF6997038.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997038.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1D02G355900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1D02G355900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1D02G355900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6997038.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997038.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus inner membrane
CC {ECO:0000256|ARBA:ARBA00004575}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004575}; Nucleoplasmic side
CC {ECO:0000256|ARBA:ARBA00004575}.
CC -!- SIMILARITY: Belongs to the NEMP family.
CC {ECO:0000256|ARBA:ARBA00005748}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022213; KAF6997038.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B5ZZ93; -.
DR STRING; 4565.A0A3B5ZZ93; -.
DR EnsemblPlants; TraesCS1D02G355900.1; TraesCS1D02G355900.1; TraesCS1D02G355900.
DR Gramene; TraesCAD_scaffold_076583_01G000200.1; TraesCAD_scaffold_076583_01G000200.1; TraesCAD_scaffold_076583_01G000200.
DR Gramene; TraesCLE_scaffold_066747_01G000200.1; TraesCLE_scaffold_066747_01G000200.1; TraesCLE_scaffold_066747_01G000200.
DR Gramene; TraesCS1D02G355900.1; TraesCS1D02G355900.1; TraesCS1D02G355900.
DR Gramene; TraesCS1D03G0836300.1; TraesCS1D03G0836300.1.CDS; TraesCS1D03G0836300.
DR Gramene; TraesPAR_scaffold_088128_01G000200.1; TraesPAR_scaffold_088128_01G000200.1; TraesPAR_scaffold_088128_01G000200.
DR Gramene; TraesWEE_scaffold_045304_01G000200.1; TraesWEE_scaffold_045304_01G000200.1; TraesWEE_scaffold_045304_01G000200.
DR OMA; IGMCPHG; -.
DR Proteomes; UP000019116; Chromosome 1D.
DR Proteomes; UP000815260; Chromosome 1D.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR019358; NEMP_fam.
DR PANTHER; PTHR31587; TRANSMEMBRANE PROTEIN (DUF2215); 1.
DR PANTHER; PTHR31587:SF4; TRANSMEMBRANE PROTEIN (DUF2215); 1.
DR Pfam; PF10225; NEMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 324..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 38433 MW; A16E6CCC0ED0514A CRC64;
MPADPSRSVV VSTEEEFLLH RVVFLVLGMV LMALAHTLSQ SLVFYYGGAM TIGIFLVVLI
ILFQGMKLLP TGRKSSLAIF AYSSVVGMTT YFLHYLSGLL RSILVEMGIA EDMHNPLGIF
LLVCVILAGA WFGFWGVRKL VLTEEGSVDA GVAYFVEWAI LIVSAVLILQ SSLDYLLAFA
ALVFCIIIKT VSRIEGMSGF MRHLSSGLSK GITRGLSRYE DLGGYSNTNG THQDGFSKLH
GEYLKHTPRR NSPLSGSQKK ISSQVLDRDS YYSTYHTTPE RRKFTKEEYE AFTKEETRKG
MQQLLSSPDF NRWALANADR ISVTPAGSGR SSSRSQERHR FFGLF
//
