ID A0A3B6A0M7_WHEAT Unreviewed; 150 AA.
AC A0A3B6A0M7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};
GN ORFNames=CFC21_013710 {ECO:0000313|EMBL:KAF6997495.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1D02G396600.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF6997495.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997495.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1D02G396600.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1D02G396600.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1D02G396600.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6997495.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997495.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact
CC DNA into chromatin, limiting DNA accessibility to the cellular
CC machineries which require DNA as a template. Histones thereby play a
CC central role in transcription regulation, DNA repair, DNA replication
CC and chromosomal stability. DNA accessibility is regulated via a complex
CC set of post-translational modifications of histones, also called
CC histone code, and nucleosome remodeling.
CC {ECO:0000256|ARBA:ARBA00002001}.
CC -!- SUBUNIT: The nucleosome is a histone octamer containing two molecules
CC each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and
CC two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of
CC DNA. {ECO:0000256|ARBA:ARBA00011538, ECO:0000256|RuleBase:RU000451}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000451}.
CC -!- SIMILARITY: Belongs to the histone H2B family.
CC {ECO:0000256|ARBA:ARBA00006846, ECO:0000256|RuleBase:RU000451}.
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DR EMBL; CM022213; KAF6997495.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6A0M7; -.
DR SMR; A0A3B6A0M7; -.
DR STRING; 4565.A0A3B6A0M7; -.
DR EnsemblPlants; TraesCS1D02G396600.1; TraesCS1D02G396600.1.cds1; TraesCS1D02G396600.
DR Gramene; TraesCAD_scaffold_027225_01G000700.1; TraesCAD_scaffold_027225_01G000700.1; TraesCAD_scaffold_027225_01G000700.
DR Gramene; TraesCLE_scaffold_029822_01G000300.1; TraesCLE_scaffold_029822_01G000300.1; TraesCLE_scaffold_029822_01G000300.
DR Gramene; TraesCS1D02G396600.1; TraesCS1D02G396600.1.cds1; TraesCS1D02G396600.
DR Gramene; TraesCS1D03G0922500.1; TraesCS1D03G0922500.1.CDS1; TraesCS1D03G0922500.
DR Gramene; TraesKAR1D01G0336360.1; cds.TraesKAR1D01G0336360.1; TraesKAR1D01G0336360.
DR Gramene; TraesPAR_scaffold_008262_01G000200.1; TraesPAR_scaffold_008262_01G000200.1; TraesPAR_scaffold_008262_01G000200.
DR Gramene; TraesROB_scaffold_007926_01G000300.1; TraesROB_scaffold_007926_01G000300.1; TraesROB_scaffold_007926_01G000300.
DR Gramene; TraesWEE_scaffold_010346_01G000300.1; TraesWEE_scaffold_010346_01G000300.1; TraesWEE_scaffold_010346_01G000300.
DR OMA; VGIMNAF; -.
DR OrthoDB; 1216773at2759; -.
DR Proteomes; UP000019116; Chromosome 1D.
DR Proteomes; UP000815260; Chromosome 1D.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR InterPro; IPR000558; Histone_H2B.
DR PANTHER; PTHR23428; HISTONE H2B; 1.
DR PANTHER; PTHR23428:SF398; HISTONE H2B.2; 1.
DR Pfam; PF00125; Histone; 1.
DR PRINTS; PR00621; HISTONEH2B.
DR SMART; SM00427; H2B; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00357; HISTONE_H2B; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|RuleBase:RU000451};
KW DNA-binding {ECO:0000256|RuleBase:RU000451};
KW Nucleosome core {ECO:0000256|RuleBase:RU000451};
KW Nucleus {ECO:0000256|RuleBase:RU000451};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 8..126
FT /note="Histone H2A/H2B/H3"
FT /evidence="ECO:0000259|Pfam:PF00125"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 150 AA; 16154 MW; 4143CA3867E6E334 CRC64;
MAPKADKKPA AESKVEKAAE KAPAGKKPKA EKRLPASKEA AGGEGKTRGR KKGSKAKKGV
ETYKIYIFKV LKQVHPDIGI SSKAMSIMNS FINDIFEKLA GESAKLARYN KKPTITSREI
QTSVRLVLPG ELAKHAVSEG TKAVTKFTSS
//
