ID A0A3B6A1M1_WHEAT Unreviewed; 329 AA.
AC A0A3B6A1M1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=HhH-GPD domain-containing protein {ECO:0000259|SMART:SM00478};
GN ORFNames=CFC21_013989 {ECO:0000313|EMBL:KAF6997811.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1D02G426100.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF6997811.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997811.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1D02G426100.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1D02G426100.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1D02G426100.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6997811.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6997811.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022213; KAF6997811.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6A1M1; -.
DR SMR; A0A3B6A1M1; -.
DR STRING; 4565.A0A3B6A1M1; -.
DR EnsemblPlants; TraesCS1D02G426100.1; TraesCS1D02G426100.1.cds1; TraesCS1D02G426100.
DR Gramene; TraesCAD_scaffold_145061_01G000100.1; TraesCAD_scaffold_145061_01G000100.1; TraesCAD_scaffold_145061_01G000100.
DR Gramene; TraesCLE_scaffold_009702_01G000200.1; TraesCLE_scaffold_009702_01G000200.1; TraesCLE_scaffold_009702_01G000200.
DR Gramene; TraesCS1D02G426100.1; TraesCS1D02G426100.1.cds1; TraesCS1D02G426100.
DR Gramene; TraesCS1D03G0981100.1; TraesCS1D03G0981100.1.CDS1; TraesCS1D03G0981100.
DR Gramene; TraesPAR_scaffold_025894_01G000100.1; TraesPAR_scaffold_025894_01G000100.1; TraesPAR_scaffold_025894_01G000100.
DR Gramene; TraesRN1D0101038900.1; TraesRN1D0101038900.1; TraesRN1D0101038900.
DR Gramene; TraesROB_scaffold_031332_01G000200.1; TraesROB_scaffold_031332_01G000200.1; TraesROB_scaffold_031332_01G000200.
DR Gramene; TraesWEE_scaffold_052307_01G000100.1; TraesWEE_scaffold_052307_01G000100.1; TraesWEE_scaffold_052307_01G000100.
DR OMA; VEMFAMF; -.
DR OrthoDB; 196492at2759; -.
DR Proteomes; UP000019116; Chromosome 1D.
DR Proteomes; UP000815260; Chromosome 1D.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0032993; C:protein-DNA complex; IBA:GO_Central.
DR GO; GO:0032131; F:alkylated DNA binding; IBA:GO_Central.
DR GO; GO:0008725; F:DNA-3-methyladenine glycosylase activity; IBA:GO_Central.
DR GO; GO:0043916; F:DNA-7-methylguanine glycosylase activity; IBA:GO_Central.
DR GO; GO:0006285; P:base-excision repair, AP site formation; IBA:GO_Central.
DR GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IBA:GO_Central.
DR CDD; cd00056; ENDO3c; 1.
DR Gene3D; 1.10.1670.40; -; 1.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR003265; HhH-GPD_domain.
DR PANTHER; PTHR43003:SF5; DNA GLYCOSYLASE SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR Pfam; PF00730; HhH-GPD; 1.
DR SMART; SM00478; ENDO3c; 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 114..269
FT /note="HhH-GPD"
FT /evidence="ECO:0000259|SMART:SM00478"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 35647 MW; 3EAB76AEDB02FE4E CRC64;
MGEQSLSQPF PHPLSPSPPA SAAATPPATA LAVSASASRP KKKPRSSGSN PAPKKPRLVP
SVRGRPLSAD GEVDAAIRHL RAADPALAPV IDAHDPPSFH CPHPPFHSLV RSVLYQQLAF
KAAASVYSRF IALVGGEAGV LPDAVLALSA EQLRQIGVSA RKASYLHDLA RKYASGILSD
DNIVAMDDRS LAAMLTMVNG IGAWSVHMFM IFSLARPDVL PSADLGIRKG VQMLYGLEDV
PRPSQMEKLC ERWRPYRSVA AWYMWRLIES KAAQTAAAMP VVPPAMPAPS EEFMLQQHQQ
QHHHHQHQQQ QQQAAIQMLD PVQMLPGLG
//
