ID A0A3B6A3U9_WHEAT Unreviewed; 936 AA.
AC A0A3B6A3U9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_014282 {ECO:0000313|EMBL:KAF6998134.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS1D02G454100.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF6998134.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6998134.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS1D02G454100.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS1D02G454100.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS1D02G454100.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6998134.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6998134.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022213; KAF6998134.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6A3U9; -.
DR STRING; 4565.A0A3B6A3U9; -.
DR EnsemblPlants; TraesCS1D02G454100.1; TraesCS1D02G454100.1.cds1; TraesCS1D02G454100.
DR Gramene; TraesCLE_scaffold_071356_01G000100.1; TraesCLE_scaffold_071356_01G000100.1; TraesCLE_scaffold_071356_01G000100.
DR Gramene; TraesCS1D02G454100.1; TraesCS1D02G454100.1.cds1; TraesCS1D02G454100.
DR Gramene; TraesCS1D03G1046800.1; TraesCS1D03G1046800.1.CDS1; TraesCS1D03G1046800.
DR Gramene; TraesKAR1D01G0360530.1; cds.TraesKAR1D01G0360530.1; TraesKAR1D01G0360530.
DR Gramene; TraesPAR_scaffold_100886_01G000100.1; TraesPAR_scaffold_100886_01G000100.1; TraesPAR_scaffold_100886_01G000100.
DR Gramene; TraesRN1D0101111000.1; TraesRN1D0101111000.1; TraesRN1D0101111000.
DR Gramene; TraesROB_scaffold_068211_01G000100.1; TraesROB_scaffold_068211_01G000100.1; TraesROB_scaffold_068211_01G000100.
DR Gramene; TraesWEE_scaffold_085496_01G000100.1; TraesWEE_scaffold_085496_01G000100.1; TraesWEE_scaffold_085496_01G000100.
DR OMA; RSSICIC; -.
DR OrthoDB; 360528at2759; -.
DR Proteomes; UP000019116; Chromosome 1D.
DR Proteomes; UP000815260; Chromosome 1D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1046; OS04G0219600 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 25..100
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 202..443
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 936 AA; 105822 MW; 635C9FAA236DAF9E CRC64;
MAEAILHALS KIGSVGLNNE VSAVRKKLSK KVASLYELPV KIEEFGVQLK AMNNVMRDFG
TTHLTNNVIK GWIADVRKLA YHVEDVIDRY SYEALKLKED GFLRWYDIRS SRHITVFSII
LEDVIQIEEE IRCVIETRKL ILEDVIQIEE EIRCVIEMRN YGSITVQSSE NEDADIGRKK
PEGSFPELVS DEDLVGIDEN RSKLTEWLTT NEEETTLITV SGMGGLGKTS LVKTVYDREK
DNFPDAHAWI VVSEIYNVVD LLAKLLTKIQ RQSPPSVDVA LGHHADVYEL TEAIQKTLQD
RKCLIVLDDV WEREAYTRMC NAFQGLQGSR VMITTRREDV AALAPRGRRL LLQPLGSVES
FKLFCSIAFH NNSPACKCPP ELEKVAAAVV RGCHGLPLAI VYSGRVLSAK EQTEHTWNQI
YNHLWSELQG NDHVQAILNR SYNDLPGYLR NCFLYCTLLP QGQPMPRESL VRLWIAEGFT
RKREDCTAEE VAEECLMELI DRNMLQVVER DEHFRVSTCK MHDIVRDLAL AVAKEQRFGS
ANDQGELMLL DTDQVRWFST CGWSDSNNTA PGGVKFTRLR TLVSIGSCSN MLSSVFSESI
YLTVLELEDS PINQVPASIG NLFHLRYIGL RRTQVRSLPD TIDKLSNLET LDLKHTRIEK
LPSGIVKAEK LRHLFADRYA DEKQTEFRYS VGVEAPKMIS RFQQLQTLET VHASKDVALQ
LKHMHGLQTV CIDSIDASSC DDLFRALSCM PQLSSLLLSA SDEEEALSFK AFEPTSTSLR
TLIVRGGWFM AGLSCPIFQE LGRYLKYLAL SWCDLEEKDP LPVLACHVPA LTYLSLNRVS
SEGILVLSAG CFPLLKTLVL KRMPDVKQLV IEEGAMPLVD GIYITTLLGM NAVPDGIDTL
GSLTKLWMLD LHREFKADWT QKQMDDKMKH VSDLRV
//
