ID A0A3B6AQ65_WHEAT Unreviewed; 165 AA.
AC A0A3B6AQ65;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Mitochondrial inner membrane protease subunit 2 {ECO:0000256|ARBA:ARBA00013650};
GN ORFNames=CFC21_014304 {ECO:0000313|EMBL:KAF6998161.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G001300.1};
RN [1] {ECO:0000313|EMBL:KAF6998161.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6998161.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G001300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G001300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2A02G001300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF6998161.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF6998161.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}.
CC -!- SIMILARITY: Belongs to the peptidase S26 family. IMP2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007066}.
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DR EMBL; CM022214; KAF6998161.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6AQ65; -.
DR SMR; A0A3B6AQ65; -.
DR STRING; 4565.A0A3B6AQ65; -.
DR EnsemblPlants; TraesCS2A02G001300.1; TraesCS2A02G001300.1; TraesCS2A02G001300.
DR Gramene; TraesCAD_scaffold_006409_01G000700.1; TraesCAD_scaffold_006409_01G000700.1; TraesCAD_scaffold_006409_01G000700.
DR Gramene; TraesCS2A02G001300.1; TraesCS2A02G001300.1; TraesCS2A02G001300.
DR Gramene; TraesCS2A03G0002200.1; TraesCS2A03G0002200.1.CDS; TraesCS2A03G0002200.
DR Gramene; TraesPAR_scaffold_028581_01G000500.1; TraesPAR_scaffold_028581_01G000500.1; TraesPAR_scaffold_028581_01G000500.
DR Gramene; TraesROB_scaffold_036898_01G000300.1; TraesROB_scaffold_036898_01G000300.1; TraesROB_scaffold_036898_01G000300.
DR Gramene; TraesWEE_scaffold_031383_01G000500.1; TraesWEE_scaffold_031383_01G000500.1; TraesWEE_scaffold_031383_01G000500.
DR OMA; MEARITH; -.
DR OrthoDB; 447775at2759; -.
DR Proteomes; UP000019116; Chromosome 2A.
DR Proteomes; UP000815260; Chromosome 2A.
DR GO; GO:0042720; C:mitochondrial inner membrane peptidase complex; IBA:GO_Central.
DR GO; GO:0004175; F:endopeptidase activity; IBA:GO_Central.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006627; P:protein processing involved in protein targeting to mitochondrion; IBA:GO_Central.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd06530; S26_SPase_I; 1.
DR Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR InterPro; IPR037730; IMP2.
DR InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR InterPro; IPR000223; Pept_S26A_signal_pept_1.
DR InterPro; IPR019757; Pept_S26A_signal_pept_1_Lys-AS.
DR InterPro; IPR019533; Peptidase_S26.
DR PANTHER; PTHR46041; MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2; 1.
DR PANTHER; PTHR46041:SF1; MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2; 1.
DR Pfam; PF10502; Peptidase_S26; 2.
DR PRINTS; PR00727; LEADERPTASE.
DR SUPFAM; SSF51306; LexA/Signal peptidase; 1.
DR PROSITE; PS00760; SPASE_I_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00022792};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 10..97
FT /note="Peptidase S26"
FT /evidence="ECO:0000259|Pfam:PF10502"
FT DOMAIN 99..141
FT /note="Peptidase S26"
FT /evidence="ECO:0000259|Pfam:PF10502"
FT ACT_SITE 37
FT /evidence="ECO:0000256|PIRSR:PIRSR600223-1"
FT ACT_SITE 82
FT /evidence="ECO:0000256|PIRSR:PIRSR600223-1"
SQ SEQUENCE 165 AA; 18122 MW; 1D297CD94AF698BB CRC64;
MAWAALRPVV KACIGGSLIG ITVSDRYFSV AAVHGGSMRP TFDGTTGGRE YAVVKRSPLY
DYSRGEVVVF VSPADHRSRT IKRLIGLPGD WVSVPDKEEI RQIPEGHCWV EGDNGTASWD
SRSYGPVPLG LVQGRVTHVL WPPSKMGRVD KRVPPEGRVM PQRNL
//
