ID A0A3B6AYG9_WHEAT Unreviewed; 465 AA.
AC A0A3B6AYG9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Arogenate dehydratase {ECO:0000256|ARBA:ARBA00013259, ECO:0000256|RuleBase:RU363004};
DE EC=4.2.1.91 {ECO:0000256|ARBA:ARBA00013259, ECO:0000256|RuleBase:RU363004};
GN ORFNames=CFC21_017278 {ECO:0000313|EMBL:KAF7001658.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G291900.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7001658.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001658.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G291900.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G291900.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2A02G291900.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7001658.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001658.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC chorismate pathway into phenylalanine. {ECO:0000256|RuleBase:RU363004}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180; EC=4.2.1.91;
CC Evidence={ECO:0000256|RuleBase:RU363004};
CC -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC phenylalanine from L-arogenate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00004929, ECO:0000256|RuleBase:RU363004}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000256|ARBA:ARBA00004470, ECO:0000256|RuleBase:RU363004}.
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DR EMBL; CM022214; KAF7001658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6AYG9; -.
DR SMR; A0A3B6AYG9; -.
DR STRING; 4565.A0A3B6AYG9; -.
DR PaxDb; 4565-Traes_2AL_6A34123EE-2; -.
DR EnsemblPlants; TraesCS2A02G291900.1; TraesCS2A02G291900.1.cds1; TraesCS2A02G291900.
DR Gramene; TraesCAD_scaffold_008114_01G000100.1; TraesCAD_scaffold_008114_01G000100.1; TraesCAD_scaffold_008114_01G000100.
DR Gramene; TraesCLE_scaffold_044851_01G000100.1; TraesCLE_scaffold_044851_01G000100.1; TraesCLE_scaffold_044851_01G000100.
DR Gramene; TraesCS2A02G291900.1; TraesCS2A02G291900.1.cds1; TraesCS2A02G291900.
DR Gramene; TraesCS2A03G0729600.1; TraesCS2A03G0729600.1.CDS1; TraesCS2A03G0729600.
DR Gramene; TraesPAR_scaffold_015031_01G000100.1; TraesPAR_scaffold_015031_01G000100.1; TraesPAR_scaffold_015031_01G000100.
DR Gramene; TraesROB_scaffold_016918_01G000100.1; TraesROB_scaffold_016918_01G000100.1; TraesROB_scaffold_016918_01G000100.
DR Gramene; TraesWEE_scaffold_068925_01G000100.1; TraesWEE_scaffold_068925_01G000100.1; TraesWEE_scaffold_068925_01G000100.
DR OMA; QGVGAIC; -.
DR UniPathway; UPA00121; UER00344.
DR Proteomes; UP000019116; Chromosome 2A.
DR Proteomes; UP000815260; Chromosome 2A.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0047769; F:arogenate dehydratase activity; IBA:GO_Central.
DR GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR GO; GO:0009094; P:L-phenylalanine biosynthetic process; IBA:GO_Central.
DR CDD; cd04905; ACT_CM-PDT; 1.
DR CDD; cd13631; PBP2_Ct-PDT_like; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR001086; Preph_deHydtase.
DR InterPro; IPR018528; Preph_deHydtase_CS.
DR PANTHER; PTHR21022:SF38; AROGENATE DEHYDRATASE; 1.
DR PANTHER; PTHR21022; PREPHENATE DEHYDRATASE P PROTEIN; 1.
DR Pfam; PF00800; PDT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU363004};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141,
KW ECO:0000256|RuleBase:RU363004};
KW Chloroplast {ECO:0000256|RuleBase:RU363004};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU363004};
KW Phenylalanine biosynthesis {ECO:0000256|ARBA:ARBA00023222,
KW ECO:0000256|RuleBase:RU363004}; Plastid {ECO:0000256|RuleBase:RU363004};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT DOMAIN 160..338
FT /note="Prephenate dehydratase"
FT /evidence="ECO:0000259|PROSITE:PS51171"
FT DOMAIN 353..443
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 465 AA; 50011 MW; BAAAD6B4FF9FE2B0 CRC64;
MPFHIPFPSQ LLAFEAAPAT SFSFLVSYSS SNSNRGSRAD WCGRLAMAVV NFVKAHIGQS
PKLQGRTPRR GSGVVRSSLQ GAVVGNRAEW LTSCAVLSSK VAALAPHSTN SHLALAVAAS
NGAVLDLIPL ETVDGSARHL PAPLRIADLS PAPMHGSELR VAYQGVPGAY SEKASGKAYP
GSDAIPCDQF EVAFQAVENW IADRAVLPVE NSLGGSIHRN YDLLLRHRLH IVGEVQLPVH
HCLLVLPGVR KEDITRVISH PQALAQCEHT LTRMPGLNAA REAFDDTAGA AEHVAANSLR
DTAAIASSRA AELYGMEVLA DGIQDDSGNV TRFVMLAREP IVPRMDRPFK TSIVFAHDKE
GTSVLFKVLS AFAFRDISLT KIESRPHRPI RLADDADSGT APKQFEYMFY VDFQASLADP
RVQNALAEVQ EFTSFLRVLG SYPMDMTPMA AGVASLDSSS AYSSS
//
