ID A0A3B6AYQ2_WHEAT Unreviewed; 525 AA.
AC A0A3B6AYQ2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Poly A polymerase head domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_017227 {ECO:0000313|EMBL:KAF7001580.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G286800.1};
RN [1] {ECO:0000313|EMBL:KAF7001580.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001580.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G286800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G286800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2A02G286800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7001580.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001580.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the tRNA nucleotidyltransferase/poly(A)
CC polymerase family. {ECO:0000256|ARBA:ARBA00007265,
CC ECO:0000256|RuleBase:RU003953}.
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DR EMBL; CM022214; KAF7001580.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6AYQ2; -.
DR EnsemblPlants; TraesCS2A02G286800.1; TraesCS2A02G286800.1; TraesCS2A02G286800.
DR Gramene; TraesCAD_scaffold_147930_01G000100.1; TraesCAD_scaffold_147930_01G000100.1; TraesCAD_scaffold_147930_01G000100.
DR Gramene; TraesCS2A02G286800.1; TraesCS2A02G286800.1; TraesCS2A02G286800.
DR Gramene; TraesCS2A03G0715600.1; TraesCS2A03G0715600.1.CDS; TraesCS2A03G0715600.
DR Gramene; TraesROB_scaffold_038791_01G000200.1; TraesROB_scaffold_038791_01G000200.1; TraesROB_scaffold_038791_01G000200.
DR Gramene; TraesWEE_scaffold_026938_01G000200.1; TraesWEE_scaffold_026938_01G000200.1; TraesWEE_scaffold_026938_01G000200.
DR Proteomes; UP000019116; Chromosome 2A.
DR Proteomes; UP000815260; Chromosome 2A.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:UniProt.
DR CDD; cd05398; NT_ClassII-CCAase; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002646; PolA_pol_head_dom.
DR InterPro; IPR032828; PolyA_RNA-bd.
DR PANTHER; PTHR43051; POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43051:SF2; POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01743; PolyA_pol; 1.
DR Pfam; PF12627; PolyA_pol_RNAbd; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81891; Poly A polymerase C-terminal region-like; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW RNA-binding {ECO:0000256|RuleBase:RU003953};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003953}.
FT DOMAIN 102..230
FT /note="Poly A polymerase head"
FT /evidence="ECO:0000259|Pfam:PF01743"
FT DOMAIN 247..308
FT /note="tRNA nucleotidyltransferase/poly(A) polymerase RNA
FT and SrmB- binding"
FT /evidence="ECO:0000259|Pfam:PF12627"
FT REGION 19..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 58596 MW; 97D77B29EC828CD5 CRC64;
MALRSPELRF AASTGLGALS RPSRLAPSPL AALASPRRRR RGPSPSPSPS PSDSNPSTAS
AGDADGPEWK KVSAKRFGYK ESMIPDEAWN VLHQLRSRGY DVYLVGGCVR DLIMKKIPKD
FDIITTADLR QVKDTFVGSA VIVGRRFPIV HVHDNNSIVE VSSFNTYVRG STGNQMPTSK
SPHCSKNDYL RWKNCQGRDF TINGLMFNPY SEKIYDYLGG IEDIKKAKVR TVIPAATSFH
EDCARLGFSF PKETAYYVRN LACSVARLDK GRLLMEVNYM LAYGSAEASL RLLWRFGLLE
HLLPFQAAYF SSTLFKRKDN GTNMLLVLFS KLDSFLAPNR PCHNSLWISI LAFHEALVRK
PRDPLVVATF ALAVYLGGDL PLAVDIGQSI NRQHDAGFAE LLEPRMRGKK GLLAEVKDLA
ISMRQALTEM TDEYYVANAM AKIPQAPSSD LVFIPLQAYL KVLKLIERVQ HGKKEIGYEP
KSDGNIDYHN LANGTPAEVR NLFTLVVFDT IYPPNLEKED DSSRR
//
