ID A0A3B6B090_WHEAT Unreviewed; 413 AA.
AC A0A3B6B090;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=CFC21_017413 {ECO:0000313|EMBL:KAF7001826.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G304300.1};
RN [1] {ECO:0000313|EMBL:KAF7001826.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001826.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G304300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G304300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2A02G304300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7001826.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7001826.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR EMBL; CM022214; KAF7001826.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6B090; -.
DR SMR; A0A3B6B090; -.
DR STRING; 4565.A0A3B6B090; -.
DR EnsemblPlants; TraesCS2A02G304300.1; TraesCS2A02G304300.1; TraesCS2A02G304300.
DR Gramene; TraesCAD_scaffold_005029_01G000100.1; TraesCAD_scaffold_005029_01G000100.1; TraesCAD_scaffold_005029_01G000100.
DR Gramene; TraesCLE_scaffold_017702_01G000200.1; TraesCLE_scaffold_017702_01G000200.1; TraesCLE_scaffold_017702_01G000200.
DR Gramene; TraesCS2A02G304300.1; TraesCS2A02G304300.1; TraesCS2A02G304300.
DR Gramene; TraesCS2A03G0758400.1; TraesCS2A03G0758400.1.CDS; TraesCS2A03G0758400.
DR Gramene; TraesKAR2A01G0329030.1; cds.TraesKAR2A01G0329030.1; TraesKAR2A01G0329030.
DR Gramene; TraesPAR_scaffold_002063_01G000100.1; TraesPAR_scaffold_002063_01G000100.1; TraesPAR_scaffold_002063_01G000100.
DR Gramene; TraesRN2A0100735800.1; TraesRN2A0100735800.1; TraesRN2A0100735800.
DR Gramene; TraesROB_scaffold_018240_01G000100.1; TraesROB_scaffold_018240_01G000100.1; TraesROB_scaffold_018240_01G000100.
DR Gramene; TraesWEE_scaffold_007940_01G000200.1; TraesWEE_scaffold_007940_01G000200.1; TraesWEE_scaffold_007940_01G000200.
DR OMA; QWEDFTE; -.
DR OrthoDB; 1053050at2759; -.
DR Proteomes; UP000019116; Chromosome 2A.
DR Proteomes; UP000815260; Chromosome 2A.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003756; F:protein disulfide isomerase activity; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:GO_Central.
DR CDD; cd02961; PDI_a_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF132; PROTEIN DISULFIDE-ISOMERASE A3; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR PRINTS; PR00421; THIOREDOXIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..413
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039989022"
FT TRANSMEM 383..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..140
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 413 AA; 46293 MW; 19F3C5C54EC7F69D CRC64;
MATTPPPPPL PLLLLPLLLL AAFSAAEEFP RDGKVIDLDD SNFEAALSSI DFLFVDFYAP
WCGHCKRLAP ELDEAAPVLV GLSEPIMVAK VNADKYRKLG SKYGVDGFPT LMLFIHGVPI
EYTGSRKADL LVRNLKKFVA PDVSTLESDS AIKSFVENAG TSFPMFIGFG VNESLIAEYG
GKYKKRAWFA VAKDFSEDWM ATYDFNKIPA LVAVHPKYNE QSVFYGPFEG RFLEDFVRQS
LLPLTVPINT ETLKLLDDDD RKVVLAILED DSDVNSTQLV KILRSAAHAN RDLVFGYVGV
KQWEEFVETF DVSKSSQLPK LLVWDRNEEY ELVEGSEKLE EGDQASQLSQ FLEGYRAGRT
IKKKVSGPSF MGFMHSLVSM NSLYILMFVV ALLGVMMYFT GQDDTQPRRV HDE
//
