ID   A0A3B6B771_WHEAT        Unreviewed;      1231 AA.
AC   A0A3B6B771;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G527400.1};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS2A02G527400.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS2A02G527400.1};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G527400.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
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DR   STRING; 4565.A0A3B6B771; -.
DR   EnsemblPlants; TraesCS2A02G527400.1; TraesCS2A02G527400.1; TraesCS2A02G527400.
DR   Gramene; TraesCS2A02G527400.1; TraesCS2A02G527400.1; TraesCS2A02G527400.
DR   OMA; PFNRITM; -.
DR   Proteomes; UP000019116; Chromosome 2A.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1180; OS02G0262800 PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          245..490
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   REGION          135..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1231 AA;  138049 MW;  384D8AE102C6A76A CRC64;
     MEMKMAVGVA NWLVGKVLTK LSDGLVSTYM ASSELGSNFL TAKNQLMYTQ ALLSASVGRD
     VGDDPGLRGL LGTLSNKADE AEDVLDELHY FMIQDEIDGT KEAAAEVGGG IKGHSIHGRH
     VARYTLGNCL PCFSSPRTQG DEPPAVAAAA AATNSEDKPG TSNDDGDVDI KLPFNRITMS
     KKIKSVIEEM NSICILVSDL LKVKTANQSS IALSTHVTTE RPPTGSIVPQ DRKLYGRSDI
     FEQTINALTS GTYHDKTLSV LPFVGPGGIG KTTFTQNLYN DEAVKGHFPV RVWVCVSTNF
     DVIRLTQEIL GCIPVTNAIT NASTVEPTNL DQLQRAISER LDSNRFLIVL DDVWTCKSER
     DWKNLLAPFT TGGTKGSMVL VTTRLPAVAH MVKTTDPIEL HGLEPDAFFA LFEACMFGRN
     KPRIYDDDLV NVARDIAKKL KGSPLAANTV GRLLKKNMSW EYWMGILEKN EWQSAKNDDD
     ILPSLQISYN YLPFHLQKCF FYCALFPEDY RFYDLKKITN FWIAMGIVDP NCQNDKNYLD
     ELVDKGFLIK DSDSDGDEYY VMHDLLHELS RNVSSQECVN ISSLSFRVSD IPQSIRHLSI
     TIEDKYDESF CQEICKLKSV IDIGNLRTLI VFQLYDSERG YILRDAFEGI KSLRVLFIAS
     LPEYLPESFS NLIHLQYLEL IVPLGERDNK HSPRTLPRFY HLRFLDLFDW HDHIIFFPKS
     ISRLVSLRHI YSSKEFHSRI PEIGKMKWLQ ELREFRVKKE SVGFELSQLG ELTELVGQLA
     IYNLETVASK REANDAKLKD KRNLKELKLI WGAGQQITDG DVLEGLQPPP NLRELGITNY
     GFAVGPSWLC SDISIKRLES LHLNGISWDT LPPFEQLPQL TNLKLENIAG MHVFGPGFGG
     LTERSFMYLK TVKIENMPEL GEXXXXXXXP LFSRLESIVC RYCPRLSSFS FLECCTNLCR
     LDIINCPKLS QIPPLPQTST LTELCVGYGF QASLSYDGKY LSADGYKGAL AFQNMDRVEV
     IRIFSSPHVS LSVSDLQRMK SLRELVAIGC ASIFSAEWFD AVVLKELAAH DKSLDEENIS
     VAAGLIPEVA ISKSSHPGSF RLEYMEVTSI SAVLIAPICR RLAATLHTLR FYYDEVTETV
     TEEQEEALHL LTCLQSLYFT CCKLRSLPRL YGLSSLRKLS IADCDGIQSL PPKEDFPTSL
     LILDVSDCCS REIKEEAEKL KEANPCLSVE K
//