ID A0A3B6B964_WHEAT Unreviewed; 681 AA.
AC A0A3B6B964;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=RBR-type E3 ubiquitin transferase {ECO:0000313|EnsemblPlants:TraesCS2A02G545900.1};
GN ORFNames=CFC21_019930 {ECO:0000313|EMBL:KAF7004748.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G545900.1};
RN [1] {ECO:0000313|EMBL:KAF7004748.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7004748.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G545900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G545900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2A02G545900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7004748.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7004748.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
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DR EMBL; CM022214; KAF7004748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6B964; -.
DR STRING; 4565.A0A3B6B964; -.
DR EnsemblPlants; TraesCS2A02G545900.1; TraesCS2A02G545900.1; TraesCS2A02G545900.
DR Gramene; TraesCS2A02G545900.1; TraesCS2A02G545900.1; TraesCS2A02G545900.
DR Gramene; TraesCS2A03G1257500.1; TraesCS2A03G1257500.1.CDS; TraesCS2A03G1257500.
DR OMA; DCEINIE; -.
DR Proteomes; UP000019116; Chromosome 2A.
DR Proteomes; UP000815260; Chromosome 2A.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd22582; BRcat_RBR_unk; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685:SF483; (WILD MALAYSIAN BANANA) HYPOTHETICAL PROTEIN; 1.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF14634; zf-RING_5; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 5.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 5.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 470..681
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 474..519
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 681 AA; 75680 MW; 216EC56A7B5CAE8C CRC64;
MATMRPQTIL LPRRIDPMFI IDGNGGSLVN GNDIGDGKHF YCAKCMSVVP CACIRPCFSM
CDHDFCSSCV AMKLPQNVAR LKCTGESSTA SEKYRGVTIL RPETVQVPSR IDPMFITDGN
EGSPVNDISD SKRFYCAKCM HVVPCACMRY NFTMCDHDFC SRCVAMKLRQ NVARVKCTGE
SSTASEEYRG VTMLQPETVQ LPSRINPMFI TDGNEGSPVN GISDSKRFYC AKCMHVVPCA
CTRYNFTMCD HNFCSRCVAM KLCQNVARVK CTGESSTVSE EYRGVTMLQP ETVLVSSRIA
PLSITDGNED SPVDDITDGK RFFCAKCMHV VPCACIRSNF TTCDHDFCSR CVGLKLCQNV
PRVKCTVDNS TVAERYHSMA MVQPETAVSS PIDPKFVTGG NEDSPLVDGN DIGDDKHFYC
AKCMHVVPCA CIRSNFRTCD HDFCSRCVAV KLGQNIAHVG YSEGEDGDDD LFYCNICMEM
VARTLKFSVN SCGHVFCSSC ITQYVAAKLD NNVARVECPD PGCKGGVVEL ERCHDIIPLD
LLDKWGFLLC ESALGTKRIY CPYRECSAPL LADSEAGVTA VREAECPHCH RLFCVRCAVP
WHGGITCNEF QKLGLDERGP EDILLRRLVG REGWQRCPKC QMYVEKSEGC NYIKCRCGYS
FCYRCASKLS ALNHFCNKCK R
//
