ID A0A3B6B9P1_WHEAT Unreviewed; 382 AA.
AC A0A3B6B9P1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=indole-3-pyruvate monooxygenase {ECO:0000256|ARBA:ARBA00039148};
DE EC=1.14.13.168 {ECO:0000256|ARBA:ARBA00039148};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2A02G587400.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS2A02G587400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2A02G587400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2A02G587400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate +
CC CO2 + H2O + NADP(+); Xref=Rhea:RHEA:34331, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:17640, ChEBI:CHEBI:30854, ChEBI:CHEBI:57783,
CC ChEBI:CHEBI:58349; EC=1.14.13.168;
CC Evidence={ECO:0000256|ARBA:ARBA00035920};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
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DR AlphaFoldDB; A0A3B6B9P1; -.
DR SMR; A0A3B6B9P1; -.
DR STRING; 4565.A0A3B6B9P1; -.
DR EnsemblPlants; TraesCS2A02G587400.1; TraesCS2A02G587400.1; TraesCS2A02G587400.
DR Gramene; TraesCS2A02G587400.1; TraesCS2A02G587400.1; TraesCS2A02G587400.
DR Gramene; TraesCS2A03G1299800.1; TraesCS2A03G1299800.1.CDS; TraesCS2A03G1299800.
DR Proteomes; UP000019116; Chromosome 2A.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IBA:GO_Central.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR000960; Flavin_mOase.
DR PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR PANTHER; PTHR43539:SF98; FLAVIN-CONTAINING MONOOXYGENASE; 1.
DR Pfam; PF13738; Pyr_redox_3; 1.
DR PIRSF; PIRSF000332; FMO; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
SQ SEQUENCE 382 AA; 41561 MW; 253405ABDC32B0C0 CRC64;
MESVAVLIVG AGPAGLATAA CLSQFAIPYV IVERESCSAS LWRNRAYDRL KLHLAKEFCE
LPHMSYPVDA PTYIPKNLFV KYLDDYVEHF NIQPKYLTYV ESSTYDNDEK CWSIVAKDMS
KCTTVKFTAK FLVVASGENS AENIPMIPGL ESFPGDVIHS SSYKSGKSYS GKNVLVVGSG
NSGMEIAYDL ATHGANTSVV IRSPIHVMTK VLIRLGMTLA HHLPLNLVDK LLVMVAYLIF
GDQSRHGITR PKMGPMTLKA ETGRSAVIDV GTVGLIKKGI IKVQGSISKI KGNIVKFQCS
KRISFDAIVF ATGYKSTANI WLKNGESMLN GNGLPIQKYP NHWKGENGLY CAGLARRGLA
GIAADAKNIA NDIKSLIDSM SS
//
