ID A0A3B6C6T1_WHEAT Unreviewed; 666 AA.
AC A0A3B6C6T1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
DE AltName: Full=Diadenosine tetraphosphate synthetase {ECO:0000256|ARBA:ARBA00030057};
GN ORFNames=CFC21_023643 {ECO:0000313|EMBL:KAF7009014.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G304900.1};
RN [1] {ECO:0000313|EMBL:KAF7009014.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009014.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G304900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G304900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G304900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7009014.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009014.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR EMBL; CM022215; KAF7009014.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6C6T1; -.
DR SMR; A0A3B6C6T1; -.
DR STRING; 4565.A0A3B6C6T1; -.
DR PaxDb; 4565-Traes_2BL_BFCA332B8-1; -.
DR EnsemblPlants; TraesCS2B02G304900.1; TraesCS2B02G304900.1; TraesCS2B02G304900.
DR Gramene; TraesCLE_scaffold_044002_01G000100.1; TraesCLE_scaffold_044002_01G000100.1; TraesCLE_scaffold_044002_01G000100.
DR Gramene; TraesCS2B02G304900.1; TraesCS2B02G304900.1; TraesCS2B02G304900.
DR Gramene; TraesCS2B03G0797500.1; TraesCS2B03G0797500.1.CDS; TraesCS2B03G0797500.
DR Gramene; TraesKAR2B01G0294630.1; cds.TraesKAR2B01G0294630.1; TraesKAR2B01G0294630.
DR Gramene; TraesPAR_scaffold_037814_01G000100.1; TraesPAR_scaffold_037814_01G000100.1; TraesPAR_scaffold_037814_01G000100.
DR Gramene; TraesROB_scaffold_143063_01G000100.1; TraesROB_scaffold_143063_01G000100.1; TraesROB_scaffold_143063_01G000100.
DR Gramene; TraesWEE_scaffold_046695_01G000100.1; TraesWEE_scaffold_046695_01G000100.1; TraesWEE_scaffold_046695_01G000100.
DR OMA; CIGKSYR; -.
DR OrthoDB; 546660at2759; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IBA:GO_Central.
DR GO; GO:0070150; P:mitochondrial glycyl-tRNA aminoacylation; IBA:GO_Central.
DR CDD; cd00774; GlyRS-like_core; 1.
DR CDD; cd00858; GlyRS_anticodon; 1.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.30.720.200; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR033731; GlyRS-like_core.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF17; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 73..542
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 666 AA; 74195 MW; B9FD53FF80E37DA3 CRC64;
MLLRLLSSAS RAIAAKPHPP QTLAAAAVGA TSTTRKLAAM AGNREAFRVA VGNTLERRLF
YVPSFKIYGG VAGLYDYGPP GCAVKANVLA FWRQHFVLEE GMLEVDCPCV TPEVVLKASG
HVEKFTDLMV KDEKTGSCYR ADHLLKDFCK EKLENDNTLS PEKVEELNHI LAVLDDLSAE
QLGAKIKEYG IVAPDTKNLL SDPYPFNLMF QTSIGPSGLS AGYMRPETAQ GIFVNFKDLY
YYNGNKLPFA AAQIGQAFRN EISPRQGLLR VREFTLAEIE HFVDPEDKSH PKFSDVSDLE
FLMFPREDQL TGRSATRLRL GEAVSEGTVN NETLGFFIGR VYLFLTQLGI DKDRLRFRQH
LPNEMAHYAA DCWDAEIECS YGWIECVGIA DRSAYDLRAH SDKSGVPLEA HEKFAEPREV
EKLVITPSKK ELGLAFKGSQ KMVLEALEAM GETEALGMKA ALESKGDVEF KVCTLGKDVT
IKRNMVSINM EKKKEHQRKF TPSVIEPSFG IGRIIYCLFE HCFYQRTGKT DDEQLNVFRF
PPLVAPIKCT VFPLVKVEKF DVVAKKISKA LTTAGISHII DITGTSIGKR YARTDEIGVP
LAITVDSTTS VTVRDRDSKD QIRVEVDEVA LVVKEVTDGQ STWADIMWRY PAHTALATDE
EEASET
//
