ID A0A3B6C6Y4_WHEAT Unreviewed; 419 AA.
AC A0A3B6C6Y4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Arogenate dehydratase {ECO:0000256|ARBA:ARBA00013259, ECO:0000256|RuleBase:RU363004};
DE EC=4.2.1.91 {ECO:0000256|ARBA:ARBA00013259, ECO:0000256|RuleBase:RU363004};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G308400.1.cds1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS2B02G308400.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G308400.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G308400.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- FUNCTION: Converts the prephenate produced from the shikimate-
CC chorismate pathway into phenylalanine. {ECO:0000256|RuleBase:RU363004}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + L-arogenate = CO2 + H2O + L-phenylalanine;
CC Xref=Rhea:RHEA:12536, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16526, ChEBI:CHEBI:58095, ChEBI:CHEBI:58180; EC=4.2.1.91;
CC Evidence={ECO:0000256|RuleBase:RU363004};
CC -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis; L-
CC phenylalanine from L-arogenate: step 1/1.
CC {ECO:0000256|ARBA:ARBA00004929, ECO:0000256|RuleBase:RU363004}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma
CC {ECO:0000256|ARBA:ARBA00004470, ECO:0000256|RuleBase:RU363004}.
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DR AlphaFoldDB; A0A3B6C6Y4; -.
DR SMR; A0A3B6C6Y4; -.
DR STRING; 4565.A0A3B6C6Y4; -.
DR PaxDb; 4565-Traes_2BL_9CDEB96B1-1; -.
DR EnsemblPlants; TraesCS2B02G308400.1; TraesCS2B02G308400.1.cds1; TraesCS2B02G308400.
DR Gramene; TraesCAD_scaffold_010347_01G000100.1; TraesCAD_scaffold_010347_01G000100.1; TraesCAD_scaffold_010347_01G000100.
DR Gramene; TraesCLE_scaffold_023470_01G000100.1; TraesCLE_scaffold_023470_01G000100.1; TraesCLE_scaffold_023470_01G000100.
DR Gramene; TraesCS2B02G308400.1; TraesCS2B02G308400.1.cds1; TraesCS2B02G308400.
DR Gramene; TraesCS2B03G0805600.1; TraesCS2B03G0805600.1.CDS1; TraesCS2B03G0805600.
DR Gramene; TraesKAR2B01G0298830.1; cds.TraesKAR2B01G0298830.1; TraesKAR2B01G0298830.
DR Gramene; TraesPAR_scaffold_000829_01G000100.1; TraesPAR_scaffold_000829_01G000100.1; TraesPAR_scaffold_000829_01G000100.
DR Gramene; TraesROB_scaffold_009444_01G000100.1; TraesROB_scaffold_009444_01G000100.1; TraesROB_scaffold_009444_01G000100.
DR Gramene; TraesWEE_scaffold_014692_01G000100.1; TraesWEE_scaffold_014692_01G000100.1; TraesWEE_scaffold_014692_01G000100.
DR OMA; AFQAVEC; -.
DR OrthoDB; 2783975at2759; -.
DR UniPathway; UPA00121; UER00344.
DR Proteomes; UP000019116; Chromosome 2B.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0047769; F:arogenate dehydratase activity; IBA:GO_Central.
DR GO; GO:0004664; F:prephenate dehydratase activity; IEA:InterPro.
DR GO; GO:0009094; P:L-phenylalanine biosynthetic process; IBA:GO_Central.
DR CDD; cd04905; ACT_CM-PDT; 1.
DR CDD; cd13631; PBP2_Ct-PDT_like; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR001086; Preph_deHydtase.
DR InterPro; IPR018528; Preph_deHydtase_CS.
DR PANTHER; PTHR21022:SF38; AROGENATE DEHYDRATASE; 1.
DR PANTHER; PTHR21022; PREPHENATE DEHYDRATASE P PROTEIN; 1.
DR Pfam; PF00800; PDT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU363004};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141,
KW ECO:0000256|RuleBase:RU363004};
KW Chloroplast {ECO:0000256|RuleBase:RU363004};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU363004};
KW Phenylalanine biosynthesis {ECO:0000256|ARBA:ARBA00023222,
KW ECO:0000256|RuleBase:RU363004}; Plastid {ECO:0000256|RuleBase:RU363004};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transit peptide {ECO:0000256|RuleBase:RU363004}.
FT DOMAIN 114..292
FT /note="Prephenate dehydratase"
FT /evidence="ECO:0000259|PROSITE:PS51171"
FT DOMAIN 307..397
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 419 AA; 44923 MW; C70CF92C03FB94BA CRC64;
MAVVNFVKPT IGQSPKLQGR TPRRGSGMVR SSLQGAVVGN RTEWLTSCAV LSSKVAALAP
HSTNSHLALA VAASNGAVLD LVPVKTVDGS ARSLPAPLRI ADLSPAPMHG SELRVAYQGV
PGAYSEKASG KAYPGSDAIP CDQFEVAFQA VENWIADRAV LPVENSLGGS IHRNYDLLLR
HRLHIVGEVQ LPVHHCLLAL PGVRKEDITR VISHPQALAQ CEHTLTRMAG LNAAREAFDD
TAGAAEYVAA NGLRDTAAIA SSRAAELYGM EVLADGIQDD SGNVTRFVML AREPIVPRMD
RPFKTSIVFA HDKEGTSVLF KVLSAFAFRD ISLTKIESRP HRPIRLVDDA DSGTAPKQFE
YMFYVDFQAS LADPRVQNAL AEVQEFTSFL RVLGSYPMDM TPMAAGVASS DSSSAYSSS
//
