ID A0A3B6C8T5_WHEAT Unreviewed; 665 AA.
AC A0A3B6C8T5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
GN ORFNames=CFC21_024218 {ECO:0000313|EMBL:KAF7009708.1}, CFC21_024219
GN {ECO:0000313|EMBL:KAF7009710.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G360400.1};
RN [1] {ECO:0000313|EMBL:KAF7009708.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009708.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G360400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G360400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G360400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7009708.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009708.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PDCD4 family.
CC {ECO:0000256|ARBA:ARBA00005497}.
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DR EMBL; CM022215; KAF7009708.1; -; Genomic_DNA.
DR EMBL; CM022215; KAF7009710.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6C8T5; -.
DR SMR; A0A3B6C8T5; -.
DR STRING; 4565.A0A3B6C8T5; -.
DR PaxDb; 4565-Traes_2BL_B09F6D195-2; -.
DR EnsemblPlants; TraesCS2B02G360400.1; TraesCS2B02G360400.1; TraesCS2B02G360400.
DR Gramene; TraesCAD_scaffold_141544_01G000100.1; TraesCAD_scaffold_141544_01G000100.1; TraesCAD_scaffold_141544_01G000100.
DR Gramene; TraesCLE_scaffold_158922_01G000100.1; TraesCLE_scaffold_158922_01G000100.1; TraesCLE_scaffold_158922_01G000100.
DR Gramene; TraesCS2B02G360400.1; TraesCS2B02G360400.1; TraesCS2B02G360400.
DR Gramene; TraesCS2B03G0928300.1; TraesCS2B03G0928300.1.CDS; TraesCS2B03G0928300.
DR Gramene; TraesKAR2B01G0346300.2; cds.TraesKAR2B01G0346300.2; TraesKAR2B01G0346300.
DR Gramene; TraesPAR_scaffold_180293_01G000100.1; TraesPAR_scaffold_180293_01G000100.1; TraesPAR_scaffold_180293_01G000100.
DR Gramene; TraesROB_scaffold_186976_01G000100.1; TraesROB_scaffold_186976_01G000100.1; TraesROB_scaffold_186976_01G000100.
DR Gramene; TraesWEE_scaffold_025598_01G000100.1; TraesWEE_scaffold_025598_01G000100.1; TraesWEE_scaffold_025598_01G000100.
DR OMA; EMQNTSS; -.
DR OrthoDB; 1217702at2759; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 4.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR039778; PDCD4.
DR PANTHER; PTHR12626:SF6; OS04G0482800 PROTEIN; 1.
DR PANTHER; PTHR12626; PROGRAMMED CELL DEATH 4; 1.
DR Pfam; PF02847; MA3; 4.
DR SMART; SM00544; MA3; 4.
DR SUPFAM; SSF48371; ARM repeat; 4.
DR PROSITE; PS51366; MI; 4.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 85..206
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 249..370
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 384..505
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 547..665
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
SQ SEQUENCE 665 AA; 73299 MW; 9A509F93FF444FA8 CRC64;
MAAEDGARSP TRMLAEGHLR IATGGRAPAD GGIAVRHIPH HHTAKKEDVG GKIEQDNLGD
ANPLPSQELG KLVNGTKKVP ATLDDYRKLV VPVIEEYFST GDVELSVSEL RSLGSDQFHN
YFVKKLISMA MDRHDKEKEM ASILLSALYA DLLDSSKMSE GFMMLLESTE DLSVDIPDAI
DVLAVFVARA IVDEILPPVF LTRARALLPE SSKGIEVLQV AEKSYLSAPH HAELVERKWG
GSTHFTVEEA KKRIQDILRE YIESGDTDEA FRCIRELGLP FFHHEVVKRA LILGMENLSS
QPLILKLLKE STTGCLISSN QVSKGFSRVA DCVDDLSLDV PSAKALFDKL LSTAMSEGWL
DASFCKSAAP DEDMWNASSE KVKRFKEESG HIIQEYFLSD DVPELIRSLE ELSAPEYNAI
FLKKLITLAM DRKNREKEMA SVLLSSLSLE LFSAGDIMKG FIMLLQSAED TALDIVDAPS
ELALFLARAV IDEVLLPLNL DDIGSKLRPN SSGSQTVQMA SSLLAARHSG ERILRCWGGG
TGWAVEDAKD KISKLLEEYN TGGDLKEACQ CIRDLGMPFF NHEVVKKALV MAMEKQNEAS
ILALLQECSS EGLITINQMT NGFARVKEGL DDLTLDIPNA QEKFRGYVEL ATERGWLLPS
FASLP
//
