ID A0A3B6C9C9_WHEAT Unreviewed; 1128 AA.
AC A0A3B6C9C9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=CFC21_024405 {ECO:0000313|EMBL:KAF7009923.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G379900.1};
RN [1] {ECO:0000313|EMBL:KAF7009923.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009923.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G379900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G379900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G379900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7009923.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009923.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022215; KAF7009923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6C9C9; -.
DR SMR; A0A3B6C9C9; -.
DR STRING; 4565.A0A3B6C9C9; -.
DR EnsemblPlants; TraesCS2B02G379900.1; TraesCS2B02G379900.1; TraesCS2B02G379900.
DR Gramene; TraesCAD_scaffold_032886_01G000100.1; TraesCAD_scaffold_032886_01G000100.1; TraesCAD_scaffold_032886_01G000100.
DR Gramene; TraesCLE_scaffold_012354_01G000100.1; TraesCLE_scaffold_012354_01G000100.1; TraesCLE_scaffold_012354_01G000100.
DR Gramene; TraesCS2B02G379900.1; TraesCS2B02G379900.1; TraesCS2B02G379900.
DR Gramene; TraesKAR2B01G0364460.1; cds.TraesKAR2B01G0364460.1; TraesKAR2B01G0364460.
DR Gramene; TraesPAR_scaffold_028219_01G000100.1; TraesPAR_scaffold_028219_01G000100.1; TraesPAR_scaffold_028219_01G000100.
DR Gramene; TraesROB_scaffold_034122_01G000100.1; TraesROB_scaffold_034122_01G000100.1; TraesROB_scaffold_034122_01G000100.
DR Gramene; TraesWEE_scaffold_029760_01G000100.1; TraesWEE_scaffold_029760_01G000100.1; TraesWEE_scaffold_029760_01G000100.
DR OMA; HEATENA; -.
DR OrthoDB; 36950at2759; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:0043504; P:mitochondrial DNA repair; IBA:GO_Central.
DR CDD; cd03243; ABC_MutS_homologs; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48360; MUTL PROTEIN ISOFORM 1; 1.
DR PANTHER; PTHR48360:SF1; MUTL PROTEIN ISOFORM 1; 1.
DR Pfam; PF01541; GIY-YIG; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00534; MUTSac; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 834..850
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
SQ SEQUENCE 1128 AA; 124402 MW; 72D70F2D78D60DB7 CRC64;
MHRLLASSVV AAAPRWLPVA DSILRRRRSC RSPLPILLFN RSWSKPRKVS RSISMVSSKV
NKQGNLCNEG MLSHIMWWKE RMESCRKPSS VQLTQRLVYS NILGLDPTLR NGSLKDGTLN
MEMLQFKSKF PREVLLCRVG DFYEAIGFDA CILVEHAGLN PFGGLRSDSI PKAGCPIMNL
RQTLDDLTRC GYSVCIVEEI QGPTQARARK GRFISGHAHP GSPYVFGLAE VDHDLEFPDP
MPVVGISRSA KGYCLISVLE TMKTYSAEEG LTEEAIVTKL RICRYHHLYL HSSLRNNSSG
TSRWGEFGEG GLLWGECNGK SFDWFDGSPI DELLCKVREI YGLDEKTSFR NVTISLEGRP
QPLYLGTATQ IGVIPTEGIP SLPKMLLPPN CAGLPSMYIR DLLLNPPSFD VASAIQEACR
LMCSITCSIP EFTCIPSAKL VRLLESKEVN HIEFCRIKNV LDEIMLMNGN TELSAIQNKL
LEPASVVTGL KVDADILIKE CRFISKRIGE VISLAGESDQ AITSSEYIPK EFFNDMESSW
KGRVKRVHAE EEFANVDVAA QALSTAVTED FLPIIVRVKA VMSSHGSSKG EISYAKEHGA
VWFKGRRLTP TVWANTPGEE QIKQLKPAID SKGRRVGEEW FTTTKVENAL ARYHEACDNA
KGKVLELLRG LSSELQDKIN ILVFCSTLLI ITKALFGHVS EGLRRGWVLP AIYPLSKDYS
MEESSSEMDL LRLFPYWLDT NQGNAILNDV NMRSLFILTG PNGGGKSSML RSVCAAALLG
VCGLMVPAAS AVIPHFDSIM LHMKAYDSPA DGKSSFQIEM SEIRSLVSRA TGRSLVLIDE
ICRGTETAKG TCIAGSIIER LDDVGCLGIV STHLHGIFDL PLSLNNTDFK AMGTEVVNGC
IQPTWRLMDG ICRESLAFQT ARKEGMPDLI IKRAEELYLT MSRSNKQTSS TANNGPSVGY
SNVNGLVDMP DGLGNMFEPP LGAFGLLRKD VESIVTAICK DKLLDLYNKR SISELVEVVC
VTVGAREQPP PSTVGRSSIY IIIRRDNKLY VGQTDDLMGR LGAHRSKEGM QDATILYIMV
PGKSIACQLE TLLINQLPSK GFKLTNKADG KHRNFGMSVT SGEAMAAH
//
