ID A0A3B6CA99_WHEAT Unreviewed; 368 AA.
AC A0A3B6CA99;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=NADP-dependent oxidoreductase domain-containing protein {ECO:0000259|Pfam:PF00248};
GN ORFNames=CFC21_023935 {ECO:0000313|EMBL:KAF7009394.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G333800.1};
RN [1] {ECO:0000313|EMBL:KAF7009394.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009394.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G333800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G333800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G333800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7009394.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7009394.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022215; KAF7009394.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6CA99; -.
DR SMR; A0A3B6CA99; -.
DR STRING; 4565.A0A3B6CA99; -.
DR PaxDb; 4565-Traes_2BL_FDFA55060-1; -.
DR EnsemblPlants; TraesCS2B02G333800.1; TraesCS2B02G333800.1; TraesCS2B02G333800.
DR Gramene; TraesCAD_scaffold_043631_01G000700.1; TraesCAD_scaffold_043631_01G000700.1; TraesCAD_scaffold_043631_01G000700.
DR Gramene; TraesCLE_scaffold_043797_01G000100.1; TraesCLE_scaffold_043797_01G000100.1; TraesCLE_scaffold_043797_01G000100.
DR Gramene; TraesCS2B02G333800.1; TraesCS2B02G333800.1; TraesCS2B02G333800.
DR Gramene; TraesCS2B03G0868300.1; TraesCS2B03G0868300.1.CDS; TraesCS2B03G0868300.
DR Gramene; TraesKAR2B01G0322100.1; cds.TraesKAR2B01G0322100.1; TraesKAR2B01G0322100.
DR Gramene; TraesPAR_scaffold_034029_01G000100.1; TraesPAR_scaffold_034029_01G000100.1; TraesPAR_scaffold_034029_01G000100.
DR Gramene; TraesROB_scaffold_130691_01G000400.1; TraesROB_scaffold_130691_01G000400.1; TraesROB_scaffold_130691_01G000400.
DR Gramene; TraesWEE_scaffold_050348_01G000600.1; TraesWEE_scaffold_050348_01G000600.1; TraesWEE_scaffold_050348_01G000600.
DR OMA; TRMGERV; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0047036; F:codeinone reductase (NADPH) activity; IEA:UniProt.
DR CDD; cd19124; AKR_AKR4A_4B; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR044497; AKR4A/B.
DR InterPro; IPR018170; Aldo/ket_reductase_CS.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR11732; ALDO/KETO REDUCTASE; 1.
DR PANTHER; PTHR11732:SF543; ALDO_KETO REDUCTASE-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 67..334
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
FT REGION 34..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 40630 MW; 087916F42D85A885 CRC64;
MAAIQPLSPF SRSSKFVGSD STIVPARILP RPRGVTRSAM ASPTGSSRSS KIPEFLAGSG
GRPVPALGIG TASFPFVAED VKNAVLAALE LGYRHLDTAS VYPSEHLVGE AVAEAGRRGV
IASREEVFVT TKVWCTQCHP DLVLPSLKES LQNLQMEYVD LYLVHWPMSV KPSKPHFPMK
REDIVQMDLK GVWQAMEECH RLGLAKMIGV SNFTTKKLQE LLAIAEIPPA VNQVELNPAW
QQKKLIEFCK EKGIHVTAYS PLGGQSRTSK VNAVLQSEIL KEIAEARGKS VAQISLRWIF
EQGASMVAKS MKKERLQENL EIFDWELTDE DRFKITRIPQ YKKVTVLAIL CPEGVPGVDL
SEVDVVET
//
