ID A0A3B6CD66_WHEAT Unreviewed; 922 AA.
AC A0A3B6CD66;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA2/NAM7 helicase-like C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_025526 {ECO:0000313|EMBL:KAF7011195.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G493400.2};
RN [1] {ECO:0000313|EMBL:KAF7011195.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7011195.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G493400.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G493400.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G493400.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7011195.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7011195.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022215; KAF7011195.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6CD66; -.
DR PaxDb; 4565-Traes_2BL_497BA0425-2; -.
DR EnsemblPlants; TraesCS2B02G493400.2; TraesCS2B02G493400.2; TraesCS2B02G493400.
DR Gramene; TraesCS2B02G493400.2; TraesCS2B02G493400.2; TraesCS2B02G493400.
DR Gramene; TraesCS2B03G1241900.2; TraesCS2B03G1241900.2.CDS; TraesCS2B03G1241900.
DR OMA; IWSIDME; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR045529; DUF6469.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF515; UVRD-LIKE HELICASE ATP-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF20073; DUF6469; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 80..186
FT /note="DUF6469"
FT /evidence="ECO:0000259|Pfam:PF20073"
FT DOMAIN 233..586
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 594..789
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 922 AA; 103862 MW; 66859000BCC8CDA6 CRC64;
MGEVDLEDLV LSWSAKEITD DDLYRGKVVT IPCNFKSLDH YLVSFRVPLI EETRSDLCSR
LQLISEAPSS KIRSMEVAGK SGLYFMDVDF WDNDAGFSTG NYTMKNGDII ILSSIKPESA
EDLSHHGVTY CLAMVTEVSM DDEYQKSFRV KVANNIGLEE DLNKLKHAIF LNNITTSMRI
WKALIFDRHM DNNFTVIKSL LAPTNLGEDV CGVCIKRDEG CLASFTEQLL SIKLNRSQVD
AIESVISAVQ CGHVNLMKLI WGPPATGKTE TVSALLWVLA CLKCRTLTCA PTNVAVVGVC
TRFLQKLKDF NEHIDENGLP FSLGDILLFG SRSNMDITDD LQEVFLDFRV DKLVECFSSS
SGWNYRIASM VSILEDCASR YDMLLEDDGK IDPVCFLDFT KKQFDATAIA LKRCIMNLWA
HLPGRCFSHD SVINISMLLK MLEKLGVLLS DIELTDEGLK RGLGCLSTAN SVCAKPISSI
EKELDEARYT CIKLLKDLLH LLNLPTGVDK NWVKNYCICN ATLLFCTTSS SYQLHHMDIA
PLDVLIVDEA AQVRECELVI SLRLHWLKYV FLVGDDCQLS AMVKSKVCKE AGFGTSLFKR
LVKLKFEKHL LNIQYRMNPC ISLFPNAQFY ERKMLDGSNV LSSSYNKDFT CLPFGSYTLI
NVTDGREDKE GTGNSRRNMV EVAIVLHLIH TIFKSWKKTG QGFSIGVVSP YNAQVDAIKT
RLGKKYDKCD GFHVRVKSIE GFQGEEDDII ILSTVRSNGT GVLGFLADNQ RTNVALTRAR
HCLWIVGNAH TLYKSGTEWT DLVADAERRK CVFSATNDAT ICRLVLQVKQ ELDELDDLLN
ADSVVFSNTR WKVILSDEFR KSFTKLKSPQ LRREILQKLI KLGAGWRTTV KNLDIPGVSH
LAKVYKVRDL YLIWSIDMEK IE
//
