ID A0A3B6CHK0_WHEAT Unreviewed; 233 AA.
AC A0A3B6CHK0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=3'-5' exonuclease domain-containing protein {ECO:0000259|SMART:SM00474};
GN ORFNames=CFC21_026881 {ECO:0000313|EMBL:KAF7012722.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2B02G625700.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7012722.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7012722.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2B02G625700.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2B02G625700.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2B02G625700.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7012722.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7012722.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022215; KAF7012722.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6CHK0; -.
DR SMR; A0A3B6CHK0; -.
DR STRING; 4565.A0A3B6CHK0; -.
DR PaxDb; 4565-Traes_2BL_31639392B-1; -.
DR EnsemblPlants; TraesCS2B02G625700.1; TraesCS2B02G625700.1.cds1; TraesCS2B02G625700.
DR Gramene; TraesCS2B02G625700.1; TraesCS2B02G625700.1.cds1; TraesCS2B02G625700.
DR Gramene; TraesCS2B03G1553500.1; TraesCS2B03G1553500.1.CDS1; TraesCS2B03G1553500.
DR Gramene; TraesWEE_scaffold_026860_01G000300.1; TraesWEE_scaffold_026860_01G000300.1; TraesWEE_scaffold_026860_01G000300.
DR OMA; SCEQIEY; -.
DR OrthoDB; 388500at2759; -.
DR Proteomes; UP000019116; Chromosome 2B.
DR Proteomes; UP000815260; Chromosome 2B.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06141; WRN_exo; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR13620:SF44; 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13620; 3-5 EXONUCLEASE; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 19..201
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00474"
FT REGION 199..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..233
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 233 AA; 26320 MW; 39F5D7A0CD25FAFD CRC64;
MGTETFVTDV AFEDDVISTT VTSSGDAVVA WLRRIRHAYR WVYHKLIVGL DVEWRPSFCR
VHNRVALLQL CVGRRCLIFP LLHADYVPRA LESFLADRDF RFVGVGVQDD ANRLSNDHGL
VVNNTVDLRG LAADGMGRPW LRQAGLKDIM GAVMGANLKK PQRVRTGAWD AHRFSHEQIK
YACIDAFVSF EVGRKLLTGD YSCSSSSDDD EEEEEEEDDS YSSDEYGSSE EDY
//
