ID A0A3B6D419_WHEAT Unreviewed; 684 AA.
AC A0A3B6D419;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_026973 {ECO:0000313|EMBL:KAF7012823.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G002400.1};
RN [1] {ECO:0000313|EMBL:KAF7012823.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7012823.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G002400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G002400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2D02G002400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7012823.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7012823.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022216; KAF7012823.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6D419; -.
DR SMR; A0A3B6D419; -.
DR STRING; 4565.A0A3B6D419; -.
DR EnsemblPlants; TraesCS2D02G002400.1; TraesCS2D02G002400.1; TraesCS2D02G002400.
DR Gramene; TraesCAD_scaffold_103960_01G000300.1; TraesCAD_scaffold_103960_01G000300.1; TraesCAD_scaffold_103960_01G000300.
DR Gramene; TraesCLE_scaffold_110289_01G000300.1; TraesCLE_scaffold_110289_01G000300.1; TraesCLE_scaffold_110289_01G000300.
DR Gramene; TraesCS2D02G002400.1; TraesCS2D02G002400.1; TraesCS2D02G002400.
DR Gramene; TraesROB_scaffold_109317_01G000300.1; TraesROB_scaffold_109317_01G000300.1; TraesROB_scaffold_109317_01G000300.
DR Gramene; TraesWEE_scaffold_103483_01G000200.1; TraesWEE_scaffold_103483_01G000200.1; TraesWEE_scaffold_103483_01G000200.
DR OMA; YPVESMG; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000815260; Chromosome 2D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF988; OS06G0707733 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 13..93
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 255..494
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 684 AA; 77122 MW; 31D88BE7B366AC7A CRC64;
MAETALGAAQ WVVSKALAPV ADGVLEAWAA TRTFGLNIQA LKTELEKVQA TLEIAATKEL
PGLATEKMLQ KLWDSAHNAE DLLDELDYFR IHDELHGTYD AADQHGDDVL RDLAFDARHT
IKALGKLVNC FPWQRAELQQ RSHGDSFSAS QANQEVSGCM PSLGKLLLSS CSPHPHVRGD
EDRGIAQETP MPEFNRADFS QRMRDTVEQL KLMRNDVKDI LQTCGHRTVL DIAQRRVTTT
PQSAEPKLYG RDHVMNNIIH DITEGQYCDK GLTVLPVIGP GGMGKTTMIQ HIYNNQQVQN
HFSVRIWICV SFNFNLGKVL EQIKEDTLTV EGENGCSTTQ ELIEHRLKHK RFLLVLDDIW
QFTDVDDWKK LLLILGKSQE KGSVILVTTR QKEIADQVKK SAEPKELNGL EPGEFKKLFL
VYVFDAEQCP GDKRFLLDTG DKIMGKLKGS PLAAKTVGRL LRTDPSLAHW KRVLNSKQWA
KQSNGIMLAL ELSYGFLPFH LQRCFSYSAL FPEDYRFRSR ELISLWIGLD ILTPSDQNPT
FEGIGLSILN DLVIHGFFRE YKTDGGLRYV MHDLLHELAL KVASHDCLRL RLPDVGSVEI
KPSTRHLSIS IENLGGYNGK KLKRELEKLK TRLKVEHLQT LMLFGAMDEG SAKIFGDFLG
EANALRVLYL PLLKYPVESM GSRS
//
