ID A0A3B6D4T9_WHEAT Unreviewed; 394 AA.
AC A0A3B6D4T9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_075829 {ECO:0000313|EMBL:KAF7070294.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G027900.2};
RN [1] {ECO:0000313|EMBL:KAF7070294.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7070294.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G027900.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G027900.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2D02G027900.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7070294.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7070294.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; CM022225; KAF7070294.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6D4T9; -.
DR SMR; A0A3B6D4T9; -.
DR STRING; 4565.A0A3B6D4T9; -.
DR EnsemblPlants; TraesCS2D02G027900.2; TraesCS2D02G027900.2; TraesCS2D02G027900.
DR Gramene; TraesCS2D02G027900.2; TraesCS2D02G027900.2; TraesCS2D02G027900.
DR Gramene; TraesCS2D03G0053600.2; TraesCS2D03G0053600.2.CDS; TraesCS2D03G0053600.
DR Gramene; TraesKAR2D01G0010920.1; cds.TraesKAR2D01G0010920.1; TraesKAR2D01G0010920.
DR OMA; LEYMEQT; -.
DR OrthoDB; 5817at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProt.
DR GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF101; CHALCONE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 8..231
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 241..391
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 167
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 394 AA; 43263 MW; 739926AD4EDDB5BC CRC64;
MAATMTVEEV RKAQRAEGPA TVLAIGTATP ANCVYQADYP DYYFKITKSD HMADLKEKFK
RMCDKSQIRK RYMHLTEEIL QDNPNMCAYM APSLDARHDI VVVEVPKLGK AAAQKAIKEW
GQPRSKITHL VFCTTSGVDM PGADYQLTKM LGLRPSVKRL MMYQQGCFAG GTVLRLAKDL
AENNRGARVL VVCSEITAVT FRGPHESHLD SLVGQALFGD GAAAVIVGAD PDMSVERPLF
ELVSASQTIL PDSEGAIDGH LREVGLTFHL LKDVPGLISK NIERALEDAF KPLGIDDWNS
VFWIAHPGGP AILDMVEAKV NLNKERMRAT RHVLSEYGNM SSACVLFIMD EMRKRSAEDG
HTTTGQGMDW GVLFGFGPGL TVETVVLHSV PITI
//
