ID A0A3B6D566_WHEAT Unreviewed; 945 AA.
AC A0A3B6D566;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7070287.1, ECO:0000313|EnsemblPlants:TraesCS2D02G028300.1};
GN ORFNames=CFC21_075825 {ECO:0000313|EMBL:KAF7070287.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G028300.1};
RN [1] {ECO:0000313|EMBL:KAF7070287.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7070287.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G028300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G028300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2D02G028300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7070287.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7070287.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022225; KAF7070287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6D566; -.
DR SMR; A0A3B6D566; -.
DR STRING; 4565.A0A3B6D566; -.
DR EnsemblPlants; TraesCS2D02G028300.1; TraesCS2D02G028300.1; TraesCS2D02G028300.
DR Gramene; TraesCLE_scaffold_006278_01G000800.1; TraesCLE_scaffold_006278_01G000800.1; TraesCLE_scaffold_006278_01G000800.
DR Gramene; TraesCS2D02G028300.1; TraesCS2D02G028300.1; TraesCS2D02G028300.
DR Gramene; TraesCS2D03G0054400.1; TraesCS2D03G0054400.1.CDS; TraesCS2D03G0054400.
DR Gramene; TraesROB_scaffold_004051_01G001200.1; TraesROB_scaffold_004051_01G001200.1; TraesROB_scaffold_004051_01G001200.
DR Gramene; TraesWEE_scaffold_010623_01G000100.1; TraesWEE_scaffold_010623_01G000100.1; TraesWEE_scaffold_010623_01G000100.
DR OMA; YANTEPH; -.
DR OrthoDB; 367540at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 7..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 192..423
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 945 AA; 106139 MW; D0BC62A0A7C65B27 CRC64;
MDLATGAMGT LLPKLLELLS EEYKLQKGVR EGVKSLEKEM RSMYAALRKV AEVPREQLDE
QVKLWAGEVR ELSFDMEDVV DKFLVHVDEG SEPAANSNKL KRLTKKMASL FTKGKVRHEI
ADAIKDINKQ VQAVAERRAR YNVDITVANL PTVTSIDPRL GAMYTEATGL VGIAGTRDQE
VMKLLSEGDD MSKKNLKIVS VVGFGGLGKT TLVKMVYEKI GGDYDCKAFV PVGRKAEAKT
VFTNILLNLG INGSELIMLN EQLLIDKLRE FLKNKRYLIV IDDIWDEKLW TIIKCAFSSS
NKFGSRLITT TRIVSVSESC SSSTNDSIYT MEPLSDDDSK RLFYKRIFSL ESGCPPDFEE
VSRDILKKCG GVPLAIITIS SLLASGQRVK PKKEWHVLLD SIGRGLTENH TAKEMIRILS
FSYYDLPSPM KTCLLYLSMF PEDSEIMKDQ LIWMWIAETF VQSGKANTSL FEVGETYFNE
LVNRSLIQPV YDDYGFVHAC HVHDSILDLI CSLSSEENFV TIVNGTSDNM SSQGNVRRLS
LQNGIKEEDR TMPHIAESIG QVRSVVTFEP AIDLMPPFSS FVVLRVLDLD EYDGTKEDHL
NLQELGRLLH LRYLRLPRHG ITELPEEIGK LKFLQVLILP GYTRLPSTVI KLTRLMCLRS
NGGRPELPDG IGKLRSMEVL NKIKVGSVSI VQELGSMHRL RELNIQFESS EPVEAFVESV
EKMQKIQRVE ISAKCEREVS MDLLGELWVP PASLWEFVMR KGVRLSMLPA WDPYHLSQLS
KLVISVGDVR QEDLELLGRL PALRILVLVS NNQRPLVVGA EGFRCLEQVG LFSKSPSQIL
FQPGALPKAE RVLLHIGLRA AKEEAAGSGG DWFDMAIGNL PSLRKVHVWF YRSGVTVGEA
KQAKAALENA LLAHPNRPSI DIDFDEYIPE DARDEDVYTE DEDSD
//
