ID A0A3B6DEA5_WHEAT Unreviewed; 805 AA.
AC A0A3B6DEA5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G308100.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS2D02G308100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G308100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G308100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476, ECO:0000256|RuleBase:RU361221}.
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DR AlphaFoldDB; A0A3B6DEA5; -.
DR SMR; A0A3B6DEA5; -.
DR STRING; 4565.A0A3B6DEA5; -.
DR PaxDb; 4565-Traes_2DL_2924C6399-1; -.
DR EnsemblPlants; TraesCS2D02G308100.1; TraesCS2D02G308100.1; TraesCS2D02G308100.
DR Gramene; TraesCAD_scaffold_013564_01G000200.1; TraesCAD_scaffold_013564_01G000200.1; TraesCAD_scaffold_013564_01G000200.
DR Gramene; TraesCLE_scaffold_011669_01G000100.1; TraesCLE_scaffold_011669_01G000100.1; TraesCLE_scaffold_011669_01G000100.
DR Gramene; TraesCS2D02G308100.1; TraesCS2D02G308100.1; TraesCS2D02G308100.
DR Gramene; TraesCS2D03G0710500.1; TraesCS2D03G0710500.1.CDS; TraesCS2D03G0710500.
DR Gramene; TraesKAR2D01G0286430.1; cds.TraesKAR2D01G0286430.1; TraesKAR2D01G0286430.
DR Gramene; TraesPAR_scaffold_012882_01G000100.1; TraesPAR_scaffold_012882_01G000100.1; TraesPAR_scaffold_012882_01G000100.
DR Gramene; TraesROB_scaffold_013988_01G000200.1; TraesROB_scaffold_013988_01G000200.1; TraesROB_scaffold_013988_01G000200.
DR Gramene; TraesWEE_scaffold_027745_01G000100.1; TraesWEE_scaffold_027745_01G000100.1; TraesWEE_scaffold_027745_01G000100.
DR OMA; EKEFHMS; -.
DR OrthoDB; 315083at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0009705; C:plant-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002251; Cl_channel_pln.
DR PANTHER; PTHR11689:SF144; CHLORIDE CHANNEL PROTEIN; 1.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01120; CLCHANNELPLT.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 119..142
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 163..189
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 209..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 279..302
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 314..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 406..427
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 486..508
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 514..533
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 545..568
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 739..800
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 805 AA; 87352 MW; BFC5708DB3A63EB7 CRC64;
MDGDHAPHSN SNQHPPPPPS PSPLPEREGS FNYDIESMDG GGWRGAGRYA SSDALLRYDD
DGPREPLLRK RTMNTTSQIA IVGANVFAIE SLDYEIVEND LFKQDWRSRK KNQIFQYVVL
KWALVLLIGL LTGLVGFFNN LAVENIAGFK LVLTGDLMLQ KRYFTAFLAY GGCNLVLGAT
AAALCAYIAP AAAGSGIPEV KAYLNGVDAY SILAPSTLFV KIFGSILGVS GGFVLGKEGP
MVHTGACIAN LLGQGGSRKY HLTWNWLKYF KNDRDRRDLI TCGAAAGVAA AFRAPVGGVL
FALEEAASWW RSALLWRTFF TTAVVAVVLR ALIEFCRKGK CGLFGQGGLI MFDLSSNVPS
YGTQDLIAII ILGVIGGVFG GLFNFLLDRI LRVYSIINER GAPSKILLTI TISIITSACS
YGLPWLAACS PCPVGSMEEC PTIGRSGNFK SFQCPPGHYN GLASLFFNTN DDAIRNLFSR
GTENEFHMSS LFVFFIAIYC LGLVTYGIAV PSGLFIPVIL AGATYGRIVG TLLGPMSDID
PGLFALLGAA SFLGGTMRMT VSVCVILLEL TNELHMLPLV MLVLLISKTI ADCFNKGVYD
QIVVMKGLPF MEAHAEPYMR HLVASDVVSG PLISFSGVEK VGNIVHALRI TGHNGFPVVD
EPPVSEAPEL VGLVLRSHVL VLLSGRNFMK EKVKTSGSFV LRRFGAFDFA KPGSGKGMKI
EDLDFTEEEM EMYVDLHPIT NTSPYTVVET MSLAKAAVLF RALGLRHLLV VPKTPGRFPI
VGILTRHDLM PEHIHGLFPN LRKSH
//
