ID A0A3B6DND8_WHEAT Unreviewed; 965 AA.
AC A0A3B6DND8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7019778.1, ECO:0000313|EnsemblPlants:TraesCS2D02G574400.1};
GN ORFNames=CFC21_032918 {ECO:0000313|EMBL:KAF7019778.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS2D02G574400.1};
RN [1] {ECO:0000313|EMBL:KAF7019778.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7019778.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS2D02G574400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS2D02G574400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS2D02G574400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7019778.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7019778.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022216; KAF7019778.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6DND8; -.
DR STRING; 4565.A0A3B6DND8; -.
DR EnsemblPlants; TraesCS2D02G574400.1; TraesCS2D02G574400.1; TraesCS2D02G574400.
DR Gramene; TraesCS2D02G574400.1; TraesCS2D02G574400.1; TraesCS2D02G574400.
DR Gramene; TraesCS2D03G1326300.1; TraesCS2D03G1326300.1.CDS; TraesCS2D03G1326300.
DR OMA; ISEECCP; -.
DR OrthoDB; 396528at2759; -.
DR Proteomes; UP000019116; Chromosome 2D.
DR Proteomes; UP000815260; Chromosome 2D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 8..97
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 176..420
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 965 AA; 109651 MW; BA81343CCFBC737F CRC64;
MDLAMGTMGS LLPKLLEVIK DEYNLQKEFK EKVKSCCTEL KAMQAALGKV AEVPRDQLDS
ETKGWADQVR ELSYEMEDVI DSLLVRVVGC DSNPNDHQNR LKKLWVSFRD LFKKGKDKHR
ISTDVKEIEK QLQKVAIQHE RYKTTNLPAV TRDPLNPLLE VLYGDKKNII GLEEARNDII
KKITEGDCKK LKTLSIVGFG GLGKTTLAKE VYDALATKFE HKAIVSVSRN PDIQKVLSDL
LFKLDQKIHA SHNAANLDVE QLTFLIRGLL SNKRYFIIID DLWDKKAWKE IRYALEDNEC
GSIIITTTRH VEISEECCPS KDYMIHKMKS LSDDDSQKLF YGRIFPSEVR PSRFEQVSKE
ILKKCAGVPL AIISLASYLA NNQNRDRIDK WKDLLNSIGS GLQNGDDHVD EMKRILLLSY
YDLPSYLKTC FLYLSIFPED HQISRDRLIR RWICEGFIQV KGQTSLLELG DAYFNELVNR
NMIMPISIHD GRVEACCVHD IMLDLICELS SQENFVTVLD FIKGDTPLEK KFRRLSLQKG
MTDPTTTRKA TTNMSQVRSF TAFSPAVSKI PSLSRFQALR VLDLEGCDLG GSPGVDLRPV
ENLLHLRYLG LRGTNVGNLS MEMAKLQFLQ TLDLQRTNSN ELPSSVVQLG HLMCLILDKG
MPLPEGFRNL TCLEQLTGDG VGIFSADSAK ELGDLIRLRE LAFKWDSRRK NPRRLFPKPD
DLRRTDEPLT HFIYGSLREN IGVLDSLDKH LTIDKALIES LGNLPELRSL EITSTGPWDA
NLMQDWVPSP NLCRFKYDGL LESLPAKICS SSLPQLSNLY LHVNKVRPED IQILGMLPAL
HYVTLMSDLG DGKNTVEQLV LGAAAFPRVR VCLFRDLLLV HPTFQLGAMP MVQRLRFGLR
VNDILSHDFD LSIRNLPSLK QLRIDLLNKE VGPEDYSQAV NVLRCVANDH PKNPTVHADK
YFRMT
//
