ID A0A3B6ED85_WHEAT Unreviewed; 995 AA.
AC A0A3B6ED85;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Histone-lysine N-methyltransferase {ECO:0000313|EnsemblPlants:TraesCS3A02G143300.2};
GN ORFNames=CFC21_112114 {ECO:0000313|EMBL:MBC2899257.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3A02G143300.2};
RN [1] {ECO:0000313|EMBL:MBC2899257.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:MBC2899257.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3A02G143300.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3A02G143300.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3A02G143300.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:MBC2899257.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:MBC2899257.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; NMPL03004140; MBC2899257.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6ED85; -.
DR SMR; A0A3B6ED85; -.
DR STRING; 4565.A0A3B6ED85; -.
DR EnsemblPlants; TraesCS3A02G143300.2; TraesCS3A02G143300.2; TraesCS3A02G143300.
DR Gramene; TraesCS3A02G143300.2; TraesCS3A02G143300.2; TraesCS3A02G143300.
DR Gramene; TraesCS3A03G0331900.2; TraesCS3A03G0331900.2.CDS; TraesCS3A03G0331900.
DR OrthoDB; 304343at2759; -.
DR Proteomes; UP000019116; Chromosome 3A.
DR Proteomes; UP000815260; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd15495; PHD_ATX3_4_5_like; 1.
DR CDD; cd15517; PHD_TCF19_like; 1.
DR CDD; cd20143; PWWP_AtATX3-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR042011; ATX3/4/5_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR025780; Hist-Lys_N-MeTrfase_ATX.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51566; SAM_MT43_TRX_MLL; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 194..263
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 380..435
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 565..616
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 619..734
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 853..970
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 979..995
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
SQ SEQUENCE 995 AA; 111956 MW; 6B0603FADFD13E50 CRC64;
MLASRIPPKR CTAAVPYELE PPAAAAEGMP PAKRRRERVL PSRFRDSAVL LPPPAKKACK
APAPPKVEDR DGQVYEVEVR AVGPKGSAFG AVQTEVWTGE PAQTEEELYR ACRNISRSGS
SGCFSGSVVT SVSNAGEKCA PEKTPVVGAV VPSTSNAGTG NVGLEGRSPV VECKPKQEAE
VRREDFYWPE DFVLGDVVWA RSGKKSPAWP ALVINPLQHA PEVVLNSCVP GALCVMFFGY
SAGGQNRDYG WVKQGMIFPF VEYLDRFQGQ SLHKLKLKPS KFRAAIEEAF LAERGFFELQ
MDGVCSLDKS VNEQSVTDGA REVTGSNNEQ ECQSHSQVVV KLAACCDSCG NRLPSKISKK
KKQETEQLLC RHCEKLLQSK QYCGICKKIW HHTDGGNWVC CDECQIWVHV ECDRTCSDLE
DLENTEYFCP DCKSKRKRVM KVEQTSTSNS SEFASTSKEK LPESIPVCCS GMEALYLPEK
HMILCECRSC KKKMMTLNEW ERHTGSRKKN WKMSIKLKGT GEPLIDLLHD IPGGNFKSST
PGIKKEELLS LQANSYSPVY AKWTTERCAV CRWVEDWDYN KIIICNRCQI AVHQECYGAR
VVQDLTNWVC RACELPQQKK ECCLCPVKGG ALKPTDIDQL WVHVMCAWYQ PKVSFPVDET
MEPAVGILSI PSEYFKKTCI ICKQMHGACT QCYKCSTYYH ATCASRAGYR MELQYSERNG
RKVTKMVSYC AFHSTPDPDN VLIVKTPDGV FSTKFLLQNN EKQSPARLAK SENHQEVFPA
EVSDCPAARC LPYEILKNKK QQGEAVAHRI MGPRHHSQDL IEALNTYMQD QKGDRPFATF
KERLQYLQRT ENKRVSCGRS GVHGWGLFAV RKIQEGQMVI EYRGDQVRRS VADLREARYH
KENKDCYLFK ISEDVVIDAT ERGNIARIIN HSCMPNCYAR IVSVGDNKSQ IILIARRDVS
AGEELTYDYK FDPDESEDRK VPCLCKAPNC RGYMN
//
