ID A0A3B6ERM0_WHEAT Unreviewed; 949 AA.
AC A0A3B6ERM0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Formin-like protein {ECO:0000256|RuleBase:RU361260};
GN ORFNames=CFC21_037280 {ECO:0000313|EMBL:KAF7025032.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3A02G397900.1};
RN [1] {ECO:0000313|EMBL:KAF7025032.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7025032.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3A02G397900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3A02G397900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3A02G397900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7025032.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7025032.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000256|ARBA:ARBA00025793}.
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DR EMBL; CM022217; KAF7025032.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6ERM0; -.
DR SMR; A0A3B6ERM0; -.
DR STRING; 4565.A0A3B6ERM0; -.
DR PaxDb; 4565-Traes_3AL_E01D0B52D-1; -.
DR EnsemblPlants; TraesCS3A02G397900.1; TraesCS3A02G397900.1; TraesCS3A02G397900.
DR Gramene; TraesCAD_scaffold_063116_01G000100.1; TraesCAD_scaffold_063116_01G000100.1; TraesCAD_scaffold_063116_01G000100.
DR Gramene; TraesCLE_scaffold_070772_01G000100.1; TraesCLE_scaffold_070772_01G000100.1; TraesCLE_scaffold_070772_01G000100.
DR Gramene; TraesCS3A02G397900.1; TraesCS3A02G397900.1; TraesCS3A02G397900.
DR Gramene; TraesCS3A03G0933100.1; TraesCS3A03G0933100.1.CDS; TraesCS3A03G0933100.
DR Gramene; TraesKAR3A01G0396410.1; cds.TraesKAR3A01G0396410.1; TraesKAR3A01G0396410.
DR Gramene; TraesPAR_scaffold_061469_01G000100.1; TraesPAR_scaffold_061469_01G000100.1; TraesPAR_scaffold_061469_01G000100.
DR Gramene; TraesROB_scaffold_033809_01G000300.1; TraesROB_scaffold_033809_01G000300.1; TraesROB_scaffold_033809_01G000300.
DR Gramene; TraesWEE_scaffold_102198_01G000100.1; TraesWEE_scaffold_102198_01G000100.1; TraesWEE_scaffold_102198_01G000100.
DR OMA; KMSTSHR; -.
DR OrthoDB; 623207at2759; -.
DR Proteomes; UP000019116; Chromosome 3A.
DR Proteomes; UP000815260; Chromosome 3A.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213:SF368; FORMIN-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23213; FORMIN-RELATED; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..949
FT /note="Formin-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039990665"
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 489..920
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 46..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 658..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 51..96
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..395
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..440
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..504
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 949 AA; 101051 MW; 1D8D365C763E5173 CRC64;
MPSLRRLPRR GLPPLLLVLL PILLAPSSSR AGVLAAPATA RRQLHQPFLP DPSSAAPPSQ
APPGPAPPFF PTLQAPPPPP GTPTAPEQPT YPALVLPNPG TPAGSATAAP SDGAGGNKSS
RSSKLVPAIL LPLLTVAVLG LSIAFFFKRR RTNAGRGVGG GCVGGGESKF LHPERASLFA
RDEFGGSGRG APATTAASTA PSAESLYVGT LAGREDGKSS DTTSSGDEVS RSSGGSPELR
PLPPLVGRQC GPAGSRSPGI GGSSPSSGDE EFYSPRGSSK ASGSQRTLAA AVQAAVAARD
RSRTPSPGSA VSTPSYPSSP GATMSPAPSS PPLLSSPGQS CRRSAKARSE SARDVFGMPP
TPPPPPPPFA PTLPPPPPPR RKPPSPSPPS SPLVSTPPAL RSATDTISKN PFTQPPAPPT
STRGQPPPPP PPPPPPLGYW ESRVRKPGMS KEAMSPALSP PPQAANSRSV PPTDAFPGRL
QDNADHGDKS EETTPRPKLK PLHWDKVRAS SDRAMVWDQL KSSSFQVNEE MIETLFICNP
ANAAPKEATK RPALPTPKAE NKVLLDPKKA QNIAILLRAL NVTKEEVCEA LCEGNTQNFG
ADLLETLLKM APTKEEEIKL REFKEETSPI KLGPSEKFLK AVLDVPFAFK RVDAMLYIAN
FESEVKYLKN NFEILEAACE ELRNSRLFLK LLEAILKTGN RMNVGTNRGD AHAFKLDTLL
KLADVKGTDG KTTLLHFVVQ EIIRTEGSRL SASNQSTPRT LANPLRDELE CKKLGLQVVA
GLGNELSSVK KAAAMDSDVL SSYVAKLAGG IEKITEVLRL NEELNTRDDA WRFHDTMQKF
LKKADDEILR VQAQESVALS LVKEITEYFH GDSAKEEAHP FRIFMVVRDF LSVLTQVCRE
VGRINDRTIA SSVRHFPVPV NPMMPQLFPR IHALRAGISD DESSVASSP
//
