ID A0A3B6FZF1_WHEAT Unreviewed; 1270 AA.
AC A0A3B6FZF1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7033760.1, ECO:0000313|EnsemblPlants:TraesCS3B02G587400.1};
GN ORFNames=CFC21_044834 {ECO:0000313|EMBL:KAF7033760.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3B02G587400.1};
RN [1] {ECO:0000313|EMBL:KAF7033760.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7033760.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3B02G587400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3B02G587400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3B02G587400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7033760.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7033760.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022218; KAF7033760.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6FZF1; -.
DR STRING; 4565.A0A3B6FZF1; -.
DR PaxDb; 4565-Traes_3B_C6FD523D7-2; -.
DR EnsemblPlants; TraesCS3B02G587400.1; TraesCS3B02G587400.1; TraesCS3B02G587400.
DR Gramene; TraesCAD_scaffold_021185_01G000100.1; TraesCAD_scaffold_021185_01G000100.1; TraesCAD_scaffold_021185_01G000100.
DR Gramene; TraesCLE_scaffold_009361_01G000100.1; TraesCLE_scaffold_009361_01G000100.1; TraesCLE_scaffold_009361_01G000100.
DR Gramene; TraesCS3B02G587400.1; TraesCS3B02G587400.1; TraesCS3B02G587400.
DR Gramene; TraesCS3B03G1468400.1; TraesCS3B03G1468400.1.CDS; TraesCS3B03G1468400.
DR Gramene; TraesROB_scaffold_011018_01G000100.1; TraesROB_scaffold_011018_01G000100.1; TraesROB_scaffold_011018_01G000100.
DR Gramene; TraesWEE_scaffold_004141_01G000500.1; TraesWEE_scaffold_004141_01G000500.1; TraesWEE_scaffold_004141_01G000500.
DR OMA; HNRVAFH; -.
DR OrthoDB; 342897at2759; -.
DR Proteomes; UP000019116; Chromosome 3B.
DR Proteomes; UP000815260; Chromosome 3B.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR36766:SF45; LRR AND NB-ARC DOMAIN DISEASE RESISTANCE PROTEIN; 1.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 14..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 185..421
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1270 AA; 142983 MW; D2DDBF8ED692D25C CRC64;
MAELVATMVV GPLLSVVKDK VSSYLLDQYK VMEGMEEQHR VLKRKLPAIL DVIDDAEQTA
SHREGAKAWL EEVKRVAYEA NGLFDEFNYE ALRREARKNG HYGELGFNAV KLLTTHNRFT
FRDRMGKKLC RIVQAIEVLV AEMNAFGFKY QQQAPESMRW RQMDHVIFDP KKIISRSRSR
DTKNIVGTLL GQANNADLSV IPIAGVGGLG KTTLAQLIYN EPEIQKHFEL LIWVCVSDSF
DVDSLAKRIV AFHLEKDVVE AAASKKSPLD SLQDVLSGHR YLLVLDDVWN RESDKWEKLK
DRLTHGANGS VVLTTTRDEG VAKIMGTVKP YNLAALEDNF IKEIIETRAF SLQKEEERLA
VLVNMVDEIV KRCRGSPLAA TALGSVLRTK TSEEEWKAIS SRSNICTEES GILPILKLSY
NDLSSQMKQC FAFCAVFPKD YEIDVDKLIQ LWIAHGFIQD HKEVSPETIG NRIFSELASS
SFFVDVKQLK ATSYERMVGG SYYKRTCKIH DLMHDVALST MENECGFAPK EPNRIEWLPD
TARHLLLSCE KPEIVLNGSL ARKSPAIQTL LCDSYMEYPL QHLSKYSTLK ALQLHTRRSP
FPFKSKHLHH LRYLDLSRSD FEALPEDISI LYNLQTLKIS GCQELRRFPR QMKYMTALRH
LYTHGCPKMR SMPGDLRKLM SLQTLTCFVA GRTGSKCSNV GELQHLNLGG QLELKQLENV
TEEDAKAANL GKKKELRELT LKWTVGSRDD ARVLECVKPH HGLQSLRIES YGGTTFPTWM
AMSRNMVEIH LSYCKNLQWL FSSGASFSFP NLKEFTLRGL ECLEGWWESS NKEQGKEVIF
PQLEKLHILD CAKLTTLPAT LLGESHGRMA RSAFPTLKVL ELRYLRSFER WDAVEGPQGA
EIMFPQLEEL YVAHCGMIKA SSGQQKVCPK LTIKAESPKL RVLEMQGSEE EMFLWIARHV
TSLTNLKLQN CEGSETTSAA AADISLRQAM SAMEKWNRHD FPLADMELIG FKSGITKLCA
CFVQLQRLCI NDCAALVHWP EKEFQSLLSL RSLNIMSCGQ LVGYAAEPST TTSESSSQLL
PRLESLKIYG CTSMVEVFRL PASLRKMTIR DCAKLRSIFS SRMPQQGQPS ASAIVQGSPP
VYSEVLPCLE EIDIRGCDGL TGGLDLPPSL KHVSVYRCSG LRSVESHSGE FPSLESLSIG
LCETLSSLPD GPRAYPSLRM LKVYDCPGMK RLPACLQQRL GSLEGITLDA HHQGPILSKP
KTWINGLCRG
//
