ID A0A3B6GL76_WHEAT Unreviewed; 758 AA.
AC A0A3B6GL76;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
GN ORFNames=CFC21_045412 {ECO:0000313|EMBL:KAF7034389.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G027400.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7034389.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034389.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G027400.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G027400.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G027400.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7034389.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034389.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022219; KAF7034389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6GL76; -.
DR STRING; 4565.A0A3B6GL76; -.
DR EnsemblPlants; TraesCS3D02G027400.1; TraesCS3D02G027400.1.cds1; TraesCS3D02G027400.
DR Gramene; TraesCLE_scaffold_032916_01G000300.1; TraesCLE_scaffold_032916_01G000300.1; TraesCLE_scaffold_032916_01G000300.
DR Gramene; TraesCS3D02G027400.1; TraesCS3D02G027400.1.cds1; TraesCS3D02G027400.
DR Gramene; TraesCS3D03G0048600.1; TraesCS3D03G0048600.1.CDS1; TraesCS3D03G0048600.
DR Gramene; TraesROB_scaffold_067210_01G000200.1; TraesROB_scaffold_067210_01G000200.1; TraesROB_scaffold_067210_01G000200.
DR Gramene; TraesWEE_scaffold_032207_01G000300.1; TraesWEE_scaffold_032207_01G000300.1; TraesWEE_scaffold_032207_01G000300.
DR OMA; ILDRCCQ; -.
DR OrthoDB; 400898at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR025315; DUF4220.
DR InterPro; IPR007658; DUF594.
DR PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR PANTHER; PTHR31325:SF121; OS09G0562750 PROTEIN; 1.
DR Pfam; PF13968; DUF4220; 1.
DR Pfam; PF04578; DUF594; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..357
FT /note="DUF4220"
FT /evidence="ECO:0000259|Pfam:PF13968"
FT REGION 210..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..580
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 83349 MW; 657278CC03597775 CRC64;
MSDIWSVVRW WDDWQLRILV LGSLGLQWFL LLAAPMRKYT IPRVFRTCIW LAYISSDALA
IYALATLFNR HARGSNCGGV EQSGVLEVLW APVLLIHLGG QQEMTGYEIE DNELWTRHTV
TLVSQVAVAL YAFCKSWRSS SDWKLLAAAV LLFVVGVLSF SEKPLALNRA KIKRLAAVSA
WVQGTKKPSK WRKRVNKFFL FEESNCFTGM PPQSSGSGGE EGAGGKKEQK PPVVALTEAD
KVLMVLSDMS LLAAAKDLVA RNKAGKVEDV LPPLPVAEKA LPRWLRSAFA FIYTRATVVV
TPLYLLYHLL VVPILHMAAL ALFAASDKHP YRRADVKITY IILCLTAALD VLAVFIRQLL
YRLMSMTKVP ALCETVPGYN LVDAALREGD KSVGWICKCA RRMGFNCKGG CLSCRPQLGQ
LYKKVAQTVI ADLVDAQDRD LASYRILDSN NWALSEELQG HCGEEIKESL RVSFDRSVLL
WHMASDLCFR CIDDAALVDD GSKQKGGEGG GGEEKDEESG AEAAEGGGGA KEIDEGSGAE
AAAAEEEGAA VEEEEATAEQ EERKSRDSRE AAAVEEEATG EGSGALRLHI KCTVAISNYM
AHLLNFNPEM LLTGSRHHLV SEAVEELKSF SLSKNKDELS QKDVNELIAG ILDRDTSSST
SQEVFHILEA CKLAKELLEI RDPTARWMLM YRVWLGMLCY SASMCRGYLH AKSLGEGGEF
LSFVWLVLSL KGAKSLADKL QMPPEASDTA KSNAPPVT
//
