ID A0A3B6GLM7_WHEAT Unreviewed; 742 AA.
AC A0A3B6GLM7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=CFC21_045534 {ECO:0000313|EMBL:KAF7034532.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G040900.1};
RN [1] {ECO:0000313|EMBL:KAF7034532.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034532.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G040900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G040900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G040900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7034532.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7034532.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CM022219; KAF7034532.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6GLM7; -.
DR SMR; A0A3B6GLM7; -.
DR STRING; 4565.A0A3B6GLM7; -.
DR EnsemblPlants; TraesCS3D02G040900.1; TraesCS3D02G040900.1; TraesCS3D02G040900.
DR Gramene; TraesCAD_scaffold_004493_01G000100.1; TraesCAD_scaffold_004493_01G000100.1; TraesCAD_scaffold_004493_01G000100.
DR Gramene; TraesCLE_scaffold_016500_01G000100.1; TraesCLE_scaffold_016500_01G000100.1; TraesCLE_scaffold_016500_01G000100.
DR Gramene; TraesCS3D02G040900.1; TraesCS3D02G040900.1; TraesCS3D02G040900.
DR Gramene; TraesCS3D03G0073200.1; TraesCS3D03G0073200.1.CDS; TraesCS3D03G0073200.
DR Gramene; TraesKAR3D01G0015700.1; cds.TraesKAR3D01G0015700.1; TraesKAR3D01G0015700.
DR Gramene; TraesPAR_scaffold_013085_01G000100.1; TraesPAR_scaffold_013085_01G000100.1; TraesPAR_scaffold_013085_01G000100.
DR Gramene; TraesROB_scaffold_013334_01G001100.1; TraesROB_scaffold_013334_01G001100.1; TraesROB_scaffold_013334_01G001100.
DR Gramene; TraesWEE_scaffold_016480_01G000100.1; TraesWEE_scaffold_016480_01G000100.1; TraesWEE_scaffold_016480_01G000100.
DR OMA; DEYMHLY; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF146; CULLIN-LIKE PROTEIN; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 388..617
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 742 AA; 86087 MW; C5486B7725FC5C32 CRC64;
MDQDQTPIAL EDGWRDMEAG IARLKRILHG VDGTSFTSQE YINLYTMIFN MCTQKPPYDY
SEQLYKRYKQ ALEEYIKSTV LPSLKSKHGE FLLRELVERW KNHKVMVRWL TRFFHYLDRY
YVSRKLLLPL KELGLSCFHD LVFGGLKTTL TTIVIDMVDN EREGQLIDRA LLKDVVGIYL
EIGQGSVGLY ELDFEKAFCK GTTDYYSKKA QIWMLEDSCP EYMLKVEDSL QKEKERVGHY
LHASTEEKLL EGTILELISW RAEEILYKEN SGCRVLLLDG KYEDLSRMYR LFSKIDAGLF
HVSKIFKEHV KEEGMSLLKH AADAANGTKN EKKEAVGSPE QEFVRKAIEL HDKQLAYVTN
CFQNNSAFHK ALKAAFEDFC NKDVAGCTSA ESLASFCDSI LRKGGSEKLS DEVVEDTFDK
VVTILSYISD KDLFVEFHRK KLGKRLLFDK SANNEHERSL LSKLKQYFGG QFTAKMEGML
NDVSTARDHQ TAFEEYMRDK LPNHRVDFSV TVLTTGFWPS YKTSNINLPS EMIKCVEIFK
DYYNSKQKSK RLTWIYSMGN CNIVAKFDAK PIELIVTTYQ AAMLLLFNGS ERLSYSEIVT
QLNLPDDDAV RLLHSLSCAK YKILNKVPSN RIISPNDVFQ VNHKFIDKMR RIKVPLPPTD
EKKKVVEDVN KDRRFSIDAS IVRIMKSRKV MGHQQLVAEC VEQLSRMFKP DIKIIKRRIE
DLISREYLER DLETANTYRY LA
//
