ID A0A3B6GPQ1_WHEAT Unreviewed; 1222 AA.
AC A0A3B6GPQ1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G119400.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS3D02G119400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G119400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G119400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
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DR AlphaFoldDB; A0A3B6GPQ1; -.
DR SMR; A0A3B6GPQ1; -.
DR STRING; 4565.A0A3B6GPQ1; -.
DR EnsemblPlants; TraesCS3D02G119400.1; TraesCS3D02G119400.1; TraesCS3D02G119400.
DR Gramene; TraesCAD_scaffold_054271_01G000200.1; TraesCAD_scaffold_054271_01G000200.1; TraesCAD_scaffold_054271_01G000200.
DR Gramene; TraesCLE_scaffold_005203_01G000200.1; TraesCLE_scaffold_005203_01G000200.1; TraesCLE_scaffold_005203_01G000200.
DR Gramene; TraesCS3D02G119400.1; TraesCS3D02G119400.1; TraesCS3D02G119400.
DR Gramene; TraesCS3D03G0248000.1; TraesCS3D03G0248000.1.CDS; TraesCS3D03G0248000.
DR Gramene; TraesKAR3D01G0062020.1; cds.TraesKAR3D01G0062020.1; TraesKAR3D01G0062020.
DR Gramene; TraesPAR_scaffold_047468_01G000200.1; TraesPAR_scaffold_047468_01G000200.1; TraesPAR_scaffold_047468_01G000200.
DR Gramene; TraesROB_scaffold_088871_01G000100.1; TraesROB_scaffold_088871_01G000100.1; TraesROB_scaffold_088871_01G000100.
DR Gramene; TraesWEE_scaffold_046026_01G000200.1; TraesWEE_scaffold_046026_01G000200.1; TraesWEE_scaffold_046026_01G000200.
DR OMA; MASKFEW; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR GO; GO:0032301; C:MutSalpha complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IBA:GO_Central.
DR GO; GO:0006298; P:mismatch repair; IBA:GO_Central.
DR CDD; cd03286; ABC_MSH6_euk; 1.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF153; DNA MISMATCH REPAIR PROTEIN MSH7; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 1044..1060
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1222 AA; 134465 MW; 5D28AD3193E28B86 CRC64;
MQPRRQQQSI RSFLHPRPSP AQEASGAGTT PERPPRPPAA SSVDGIMERL VRPPSQGRNK
DATQIRNAER ALPGKNEDTS NEQPSASFPV RYNGKYSRGT VLFAEHSTDT TPPQEPLKFS
ARSSTDEFVR ASTLFPEIGS DQTLLQECPK KLSSECPSNQ YVQANSVFEA FDVQTPSQDP
LKRIFSGPFH GADTPLSEYR SYPIPLQHPS KKLSSGSSSG EYLRAVTPLG LDSNDTPTAK
HSKKLFSGSS DHSYIKATNL FPEFDSNGTP LQNHSNKFSV SMNSKNIGAP ATLFPELDSV
LLKPETPVTQ AVAPRGKRVQ QDQCMTANNC QSPLWGSNKK VKSAHCSPAG KMVHDEMAES
ARSKFEWLNP LNIRDANKRR PDDPLYDKRT LFIPPDALRK MSTSQKQYWT IKCKYMDVLL
FFKVGKFYEL YEVDAEIGQK ELDWKMTISG VGKCRQVGIS ESGIDNAVEK LLARGYKVGR
IEQMESAAQA KARGPNSVIE RKLAHVSTPS TAADSNIGPD AVHLLALKEV TLASNGSRVY
GFAFLDYAAL KIWVGSLQDD DSSAALGALL VQVSPREIIY ESSGLSRESR KSMIKYASAG
SVKMQLTPLP GTDFSDASQI QMLVHSKGYF KASTDSWLSA LDYSVNQDAV ICALGGLIGH
LTRLMLDDAL KNGEVLPYNV YQTCLRMDGQ TLVNLEIFGN NFDGGSSGTL YKHLNHCITA
SGKRLLRRWI CHPLKDVDAI NRRLDIVEGF IQHCGVGSVT LEHLRKIPDL ERLLGRVRST
VGLTSAVLLP FVGEKILKRR IKTFCMLIKG LRVAIDLLSA LRREDHGIPA LSKSVDIPTL
SSLDESVHQF EEAIRIDFEQ YQDHDIKDHD ATTLANLVEH FVGKATEWSL VINAISTVDV
LRSFAAMALS SFGTMCRPRI LLKDKSPILR MKGLWHPYAF AESGTGLVPN DLSLGQDLLG
HNRFALLLTG PNMGGKSTIM RATCLAIVLA QLGCYVPCIS CELTLADSIF TRLGATDRIM
SGESTFLVEC SETASVLQNA TEDSLVLLDE LGRGTSTFDG YAIAYAVFRH LVEQVRCRLL
FATHYHPLTK EFASHPHVSL QHMACMLRPR SGGNGEMELT FLYRLVSGAS PESYGLQVAT
MAGIPKSIVE KAAVAGEMMK SRIAGNFRSS EGRAEFSTLH EDWLQTILAI GGVKDAHLDE
DTMDTMFCVA QELKSHFRKG GS
//
