ID A0A3B6GUC1_WHEAT Unreviewed; 625 AA.
AC A0A3B6GUC1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Transcription factor {ECO:0000256|RuleBase:RU369104};
DE Short=bHLH transcription factor {ECO:0000256|RuleBase:RU369104};
DE AltName: Full=Basic helix-loop-helix protein {ECO:0000256|RuleBase:RU369104};
GN ORFNames=CFC21_046773 {ECO:0000313|EMBL:KAF7036009.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G166300.2};
RN [1] {ECO:0000313|EMBL:KAF7036009.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7036009.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G166300.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G166300.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G166300.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7036009.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7036009.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369104}.
CC -!- SIMILARITY: Belongs to the bHLH protein family.
CC {ECO:0000256|ARBA:ARBA00005510}.
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DR EMBL; CM022219; KAF7036009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6GUC1; -.
DR SMR; A0A3B6GUC1; -.
DR STRING; 4565.A0A3B6GUC1; -.
DR EnsemblPlants; TraesCS3D02G166300.2; TraesCS3D02G166300.2; TraesCS3D02G166300.
DR Gramene; TraesCS3D02G166300.2; TraesCS3D02G166300.2; TraesCS3D02G166300.
DR Gramene; TraesCS3D03G0356700.1; TraesCS3D03G0356700.1.CDS; TraesCS3D03G0356700.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd11449; bHLH_AtAIB_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR045084; AIB/MYC-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR025610; MYC/MYB_N.
DR PANTHER; PTHR11514; MYC; 1.
DR PANTHER; PTHR11514:SF47; TRANSCRIPTION FACTOR BHLH13; 1.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|RuleBase:RU369104};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369104};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU369104}.
FT DOMAIN 467..516
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 438..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 68314 MW; 3633DDAB580CF1C1 CRC64;
MPSYTGLMVM KMEVEEDGAN GGNGGAWTEE DRDLSTTVLG RDAFAYLTKG GGTISEGLVA
ASSPVDLQNK LQELIESEHP GAGWNYAIFW QLSRTKSGDL VLGWGDGSCR EPNDAELAAA
ASAGNDDAKQ RMRKRVLQRL HRAFGAADEE DYAPTIGQVT DTEMFFLASM YFAFPRRAGA
PGQVFAAGLP LWVPNSERNV FPANYCYRGY LASTAGFRTI LLVPFETGVL ELGSMQQVAE
SSDTLQTIKS VFAGTGGNKD IIPSREGNGH IERSPGLAKI FGKDLNLGRS SAGPVIGVSK
VDERSWEQRT AGGGSSVLPN VQKGLQSFTW SQARGLNSHQ QKFGNGILIV SNEATHGNNR
ATDSSTTTQF QLQKAPQLQK LPLLQKPPQL VKPLQMVNQQ QLQPQAPRQI DFSAGTSSKS
GVLVTRAAVL DGDSSEVNGL CKEEGTTPVI EDRRPRKRGR KPANGREEPL NHVEAERQRR
EKLNQRFYAL RAVVPNISKM DKASLLGDAI AYITDLQKKL KDMETERERF LESGMVDPRE
RAPRPEVDIQ VVQDEVLVRV MSPLENHPVK KVFEAFEEAD VRVGESKLTG NNGTVVHSFI
IKCPGSEQQT REKVIAAMSR AMSSV
//
