ID A0A3B6GUS4_WHEAT Unreviewed; 1160 AA.
AC A0A3B6GUS4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=CFC21_080812 {ECO:0000313|EMBL:KAF7076117.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G251400.7};
RN [1] {ECO:0000313|EMBL:KAF7076117.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7076117.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G251400.7}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G251400.7};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G251400.7}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7076117.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7076117.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022225; KAF7076117.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6GUS4; -.
DR EnsemblPlants; TraesCS3D02G251400.7; TraesCS3D02G251400.7; TraesCS3D02G251400.
DR Gramene; TraesCS3D02G251400.7; TraesCS3D02G251400.7; TraesCS3D02G251400.
DR Gramene; TraesCS3D03G0589900.5; TraesCS3D03G0589900.5.CDS; TraesCS3D03G0589900.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR47989:SF44; OS01G0709500 PROTEIN; 1.
DR PANTHER; PTHR47989; OS01G0750732 PROTEIN; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 696..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 785..1061
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 120..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..207
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 813
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1160 AA; 124671 MW; 07FF81A3D6431FC8 CRC64;
MGRRQGGNGW GVCAALAVAS VVSAVVILGG AGHQQSHAPA FGRKVLLSIT SGHPQINLDN
ILHPSQLQVP TLQSLGLTVK LSAPTSTDVN KQYDHYAPSP TIKHEDETVS ASKQAVLPTM
QPSVSPDHFY QSPEISPSIQ SPGQPAPPSL MVSPATQRGN HHLQEQMSAA SPSLPVEPHV
SHAKIAVNTP AAAPFLPQPP WSSQPPPSSP STGSQSTQPA PLHRIYGHCQ DTLRVPVASP
SEELPSNKKP PQEVVPPAPI APGSSQDKDG ISFARPPNNL PIHSSSPPKG TRETNHLTPA
VPPLIHRAIQ TPPQQRQHPH SNGPVASPRT TIHPANHGKA NRVPVASPLK GRHHHSIPVN
NTHGISGAPV VAPSKGRHHR SLPVNRTSVE GPVVSPQISP SIRRRGHVIP VAAPPKEPSS
HVPPANHKHH KGSFPVISPA PHRTGNASAT SHGHSGLDHG PAPAPLVLPP SNGKDGNPAY
APHHPRQYHS PSYSPEPALP PDNPAFRKPR ALAPAPSHSL PPPPPPPNSY CTALNCKDPM
TNSPPGTTCL CVLPIKVELR LGIALYTFFA LVSELAQEIA SGVFMKQSQV HVMGANAATE
DPEKTIVLID LVPLGASFDN TTTLSVFERF WHKQVIINPT DFGNYDVLYV QYPGLPSSPP
SAPGNLNNSL SNGNDQRLHP LAADIGNHRE TKSRGIIVII VLSSVFALIL CAGAALVIYF
KLRNRHHLTE ASLIPEKPAD SAIAGSRLES RPISASPSLS SSIVAYKGSA KIFSLVEMDR
ATQRFDESRI IGEGGFGRVY EGILEDGERV AVKVLKRDDQ QGTREFLAEV EMLSRLHHRN
LVKLIGICSE EHMRCLVYEL VPNGSLEFHL HGSYKDTALL DWDARLKIAL GAARGLAYLH
EDSSPRVIHR DFKSSNILLE HDFTPKVSDF GLARTAIGEG NEHISTRVMG TFGYVAPEYA
MTGHLLVKSD VYSYGVVLLE LLTGRKPVDM SRPPGQENLV TWACPFLTNR DGLETLIDAS
LGSSIPLDSI AKVAAIASMC VQPEVDQRPF MGEVVQALKL VCKEGSEFNE STSFSQDLHI
QDAEIVSRAS LDMDAGPVLS TEQFTASARY DTLDASGSFR RYSSSGPLKV GRTEHNRERG
LSTGSSSEHC GLQRFRMDSE
//
