ID A0A3B6H0N6_WHEAT Unreviewed; 469 AA.
AC A0A3B6H0N6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(+)] {ECO:0000256|RuleBase:RU361243};
DE EC=1.1.1.8 {ECO:0000256|RuleBase:RU361243};
GN ORFNames=CFC21_048414 {ECO:0000313|EMBL:KAF7038208.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G324000.1};
RN [1] {ECO:0000313|EMBL:KAF7038208.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7038208.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G324000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G324000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G324000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7038208.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7038208.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate
CC + H(+) + NADH; Xref=Rhea:RHEA:11092, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57540, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642,
CC ChEBI:CHEBI:57945; EC=1.1.1.8;
CC Evidence={ECO:0000256|RuleBase:RU361243};
CC -!- SIMILARITY: Belongs to the NAD-dependent glycerol-3-phosphate
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00011009,
CC ECO:0000256|RuleBase:RU000437}.
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DR EMBL; CM022219; KAF7038208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6H0N6; -.
DR STRING; 4565.A0A3B6H0N6; -.
DR EnsemblPlants; TraesCS3D02G324000.1; TraesCS3D02G324000.1; TraesCS3D02G324000.
DR Gramene; TraesCAD_scaffold_010221_01G000100.1; TraesCAD_scaffold_010221_01G000100.1; TraesCAD_scaffold_010221_01G000100.
DR Gramene; TraesCLE_scaffold_064532_01G000100.1; TraesCLE_scaffold_064532_01G000100.1; TraesCLE_scaffold_064532_01G000100.
DR Gramene; TraesCS3D02G324000.1; TraesCS3D02G324000.1; TraesCS3D02G324000.
DR Gramene; TraesCS3D03G0731900.1; TraesCS3D03G0731900.1.CDS; TraesCS3D03G0731900.
DR Gramene; TraesKAR3D01G0317440.1; cds.TraesKAR3D01G0317440.1; TraesKAR3D01G0317440.
DR Gramene; TraesPAR_scaffold_075430_01G000100.1; TraesPAR_scaffold_075430_01G000100.1; TraesPAR_scaffold_075430_01G000100.
DR Gramene; TraesRN3B0100914800.1; TraesRN3B0100914800.1; TraesRN3B0100914800.
DR Gramene; TraesRN3D0100764400.1; TraesRN3D0100764400.1; TraesRN3D0100764400.
DR Gramene; TraesWEE_scaffold_068302_01G000100.1; TraesWEE_scaffold_068302_01G000100.1; TraesWEE_scaffold_068302_01G000100.
DR OrthoDB; 1201464at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0047952; F:glycerol-3-phosphate dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IBA:GO_Central.
DR GO; GO:0006116; P:NADH oxidation; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006168; G3P_DH_NAD-dep.
DR InterPro; IPR006109; G3P_DH_NAD-dep_C.
DR InterPro; IPR011128; G3P_DH_NAD-dep_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11728; GLYCEROL-3-PHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11728:SF38; GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)] 2, CYTOSOLIC-RELATED; 1.
DR Pfam; PF07479; NAD_Gly3P_dh_C; 1.
DR Pfam; PF01210; NAD_Gly3P_dh_N; 1.
DR PRINTS; PR00077; GPDHDRGNASE.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|RuleBase:RU000437};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU000437};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 147..250
FT /note="Glycerol-3-phosphate dehydrogenase NAD-dependent N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF01210"
FT DOMAIN 275..428
FT /note="Glycerol-3-phosphate dehydrogenase NAD-dependent C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07479"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 469 AA; 51724 MW; B521B696B8FB04B3 CRC64;
MGGAEDGAHA AGGHASNGHA NGAVEEKVDE LRRVMGKADG DPLRIVGVGA GAWGSVFCAL
LQDAYGHLRD KVQLRIWRRP GRAVDRATAE HLFNVINARE DVLRRLIRRC AYLKYVEGRL
GDRTLYADEI LRDGFCLNMI DTPLCPLKVV TNLQEAVWDA DIVINGLPST ETRVVFGEIG
RYWKERVNAP VIISLTKGIE ASLDPVPRII TPTQMISKAT KVPLDNILYL GGPNIASEIY
NKEYANARIC GTDKWRKPLA KFLRQPHFIV WDNSDLITHE VMGGLKNVYA IGAGMVAALT
NESATSKSVY FALCTSEMIY ITHLLEEEPE KLAGPLLADT YVTLLKGRNA WYGHKLAKGE
LTLEMGDSIK GKGTIQGVSA VDAFYKLLSQ DSLSVMHPEA NKSVAPVEMC PILKTLHKIL
IKRELPTESI LQAIRDESMC DPRERIEMAR GQSLYRPSIL GQPNGDVKA
//
