ID A0A3B6H193_WHEAT Unreviewed; 802 AA.
AC A0A3B6H193;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G354500.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS3D02G354500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G354500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G354500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- FUNCTION: Probable ATP-dependent zinc metallopeptidase.
CC {ECO:0000256|ARBA:ARBA00003497}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
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DR AlphaFoldDB; A0A3B6H193; -.
DR SMR; A0A3B6H193; -.
DR STRING; 4565.A0A3B6H193; -.
DR EnsemblPlants; TraesCS3D02G354500.1; TraesCS3D02G354500.1; TraesCS3D02G354500.
DR Gramene; TraesCLE_scaffold_033430_01G000100.1; TraesCLE_scaffold_033430_01G000100.1; TraesCLE_scaffold_033430_01G000100.
DR Gramene; TraesCS3D02G354500.1; TraesCS3D02G354500.1; TraesCS3D02G354500.
DR Gramene; TraesCS3D03G0785200.2; TraesCS3D03G0785200.2.CDS; TraesCS3D03G0785200.
DR Gramene; TraesKAR3D01G0337400.1; cds.TraesKAR3D01G0337400.1; TraesKAR3D01G0337400.
DR Gramene; TraesPAR_scaffold_037552_01G000100.1; TraesPAR_scaffold_037552_01G000100.1; TraesPAR_scaffold_037552_01G000100.
DR Gramene; TraesROB_scaffold_039791_01G000100.1; TraesROB_scaffold_039791_01G000100.1; TraesROB_scaffold_039791_01G000100.
DR Gramene; TraesWEE_scaffold_030220_01G000500.1; TraesWEE_scaffold_030220_01G000500.1; TraesWEE_scaffold_030220_01G000500.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR GO; GO:0005745; C:m-AAA complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0034982; P:mitochondrial protein processing; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.1690.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR PANTHER; PTHR43655:SF25; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 3, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 355..495
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 22..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 802 AA; 87573 MW; 4241E84042CFF183 CRC64;
MSLSALSRAL ARSSRSRQGY LLGGHGVLRA PLPSPSPPPS PLLPGGEGAG LRLVRRYLTS
ALGSRASSAN AAGKVRDGRS LLANSQSRRL LSDQSKKNFP KEKEVPQGDG SNKSESKKES
NSGGQPNVQE KLLKLFQDSI GPVFLLGLLL ATLSGSSEKE ISFQEFKNKL LEPGLVDRIV
VINKTVAKVH VRSSPSTKQN QHSDTSITTS HLPGQEAPSK YKYYFNIGSV DSFEEKLEEA
QEALGIDRHD YIPVIYADKI SWFQEIMKFA PTLFIVGLLY VVGRKMSISI GSGSGQGGRS
IFSIGKAQVT KMDKNSKNKV FFKDVAGCDE AKQEIMEFVH FLKNPDKYEA LGAKIPKGAL
LCGPPGTGKT LLAKATAGES GVPFLSISGS DFLEMFVGVG PSRVRSLFQE ARECAPSIVF
IDEIDAIGRA RGRGGYSGGN SERENTLNQL LVEMDGFGTT AGVVVLAGTN RPDILDKALL
RPGRFDRQIS IDRPDINGRE QIFRIYLAKL KLDKEPSFYS QRLAALTPGF AGADIANICN
EAALITARRD EKLITMQHFE SAIDRVIGGL EKKNTVISKL ERRTVAYHES GHAVAGWFLE
HAEPLLKVTI VPRGTAALGF AQYVPSENLL MTKEQFFDRT CMTLGGRAAE EVLIGKISTG
AQNDLEKVTK MTYEQVAVYG FSEKVGLLSF PQRYDGFGMD KPYSGQTASM IDTEVRELVA
KAYNTTTELI RKHKDKVAQV AELLLEKEVL HQDDLVRVLG ERPFKTAEPT NYDRFKQGFM
DSEDSKSAEV DPSSSVGEAV PT
//
