ID A0A3B6H557_WHEAT Unreviewed; 1506 AA.
AC A0A3B6H557;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7039976.1, ECO:0000313|EnsemblPlants:TraesCS3D02G468800.1};
GN ORFNames=CFC21_049913 {ECO:0000313|EMBL:KAF7039976.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G468800.1};
RN [1] {ECO:0000313|EMBL:KAF7039976.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7039976.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G468800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G468800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G468800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7039976.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7039976.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022219; KAF7039976.1; -; Genomic_DNA.
DR STRING; 4565.A0A3B6H557; -.
DR PaxDb; 4565-Traes_3DL_8B35453E5-1; -.
DR EnsemblPlants; TraesCS3D02G468800.1; TraesCS3D02G468800.1; TraesCS3D02G468800.
DR Gramene; TraesCAD_scaffold_067765_01G000100.1; TraesCAD_scaffold_067765_01G000100.1; TraesCAD_scaffold_067765_01G000100.
DR Gramene; TraesCLE_scaffold_047487_01G000100.1; TraesCLE_scaffold_047487_01G000100.1; TraesCLE_scaffold_047487_01G000100.
DR Gramene; TraesCS3D02G468800.1; TraesCS3D02G468800.1; TraesCS3D02G468800.
DR Gramene; TraesCS3D03G1032300.1; TraesCS3D03G1032300.1.CDS; TraesCS3D03G1032300.
DR Gramene; TraesPAR_scaffold_033916_01G000200.1; TraesPAR_scaffold_033916_01G000200.1; TraesPAR_scaffold_033916_01G000200.
DR OMA; YWVTGIS; -.
DR OrthoDB; 402487at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR PANTHER; PTHR36766:SF3; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 17..99
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 174..427
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 38..65
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1506 AA; 170060 MW; EF41BE643F21A347 CRC64;
MAAVGGLIAR AVGNQIASKL GELVKDEIAL LWGFQDDVEG LREKMEDLDA LMRDADDRLR
RGERDGEAVG RWLAKFKAVA YDIEDVLDDL DATKLVLKTQ SKVKLFFSGN NQLLQRSTIA
HNMKTVREKI EKIEKEGQAL NLVRHVARAE GSRNKETFAA CSTQGMKTAM VGRDTEKEKI
INLLLTSEAN EGISIIPIIG LGGIGKSTLA EAVLADKRVS VFDVQIWVHV SEQFDLHTIG
SRIIRRLNSN INLDKCDLQF IHDNLKKELS TIRYLIVLDD LWEEDGNNLE ELKRILQCGC
KGSRIIVTTR NQSIVQTLRT GFLAKDQKIC PVPESDQISL GVLSPDDCWE VMKQRALGPN
DDHSGLQEIG REIAAKCGGL PIVANALGQV MFERRTVEAW EDIRDTKVDL GLREEHQNKA
LERLMLSYCY MKLEFKMCFT YLAVFPKGSV MDQHHLIQQW TALGYIKAYD DGERCINYLL
GMSFLHISQS SSVDPGPMHA KTSQKFTMHD LVHDLASVIT SKEFIILDAD ATEPRGWNRA
RYCRHAQLIN YQNQTTVFKD LPPTARTLHF RYSGKLQLPK MAFSRSKYIR VLDLSGHSVG
RQSTSSNLDL HGSSVEGQST SSNVVLPSSI HKSKLLRYLD ATSLPITSLP KSFHTLKHMQ
TLILSKCALE TLPDTICSLN KLCYLDLSGN VSLTELPASL GKLSKLSFIN LLGCSVLQEL
PESIYELTCL RHLDMSECCT IKKLPDKFGT LLKLIFLNLS GCSKITNLPD NLRLQSLEHM
NLSNCHELEN LPKDFGNLQR LRFLSLSDCY KVSLLPESFC QLIHLKFLDL SDCHELMELP
ECFGHLFELD SLNLTSCCKL QVLPESFCKL SKLRCLSLSY CMRLDKLPPS FGDLKLQSLD
ISSTESLNAL PDSIAEMTSL TRFEAMAGAP DVMARVEEIK KHLIISEEIK HVVQQRENKG
CSSIVELADL TCYELDVQEL QNVKHPEDAE RAKLRDKSDL RQLTLHWGTN GGEGKSVLEK
LTPPRTLDYF YLFGYMSKDF PKWMCDISSY LPSLTYLSLS DLGTCDTLPP FGQLPNLRSI
CMEKMPNIRK IGKEFFGQGR PCVKLRSIML ELMENLTELW TTRSGEENEE FLIPNLHSLC
VSNCPKLKFL PYPPRSMIWY LENTDEIIAE GGFGKLSSSA LPFHMVINNC SFSPDNWDRL
HHFPTLEVFQ VESCKGLRAL PEVIRCFTSL KSLVLKSLKE LESLPKWLGC FISLQRLLIK
DCPKLTSLPE SMKNLTALKL LQLQGCKGWE ILPEWIGKLT SLQDFQIIDC PNLTFLPESM
KGLTSLTELW IEECQGLAML PESLGQIISL QKFQIIDCPN LTTLPESMKG LTSLTELWIE
ECQGLAMLPE CLGQMISLQK FCIIDCPNLT FLPESMKKLT ALRVLSLKEC QRLHMLPEWL
QELTSLEEFN IMDCPNLISL PQSIQNLPVL KELYIWGCPI LVERCQGEDA GLISQIPEVT
LHVPEE
//
