ID A0A3B6H561_WHEAT Unreviewed; 1553 AA.
AC A0A3B6H561;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7039979.1, ECO:0000313|EnsemblPlants:TraesCS3D02G469200.1};
GN ORFNames=CFC21_049916 {ECO:0000313|EMBL:KAF7039979.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G469200.1};
RN [1] {ECO:0000313|EMBL:KAF7039979.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7039979.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G469200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G469200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G469200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7039979.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7039979.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022219; KAF7039979.1; -; Genomic_DNA.
DR STRING; 4565.A0A3B6H561; -.
DR PaxDb; 4565-Traes_3DL_39582CAD6-1; -.
DR EnsemblPlants; TraesCS3D02G469200.1; TraesCS3D02G469200.1; TraesCS3D02G469200.
DR Gramene; TraesCAD_scaffold_055449_01G000100.1; TraesCAD_scaffold_055449_01G000100.1; TraesCAD_scaffold_055449_01G000100.
DR Gramene; TraesCLE_scaffold_062540_01G000100.1; TraesCLE_scaffold_062540_01G000100.1; TraesCLE_scaffold_062540_01G000100.
DR Gramene; TraesCS3D02G469200.1; TraesCS3D02G469200.1; TraesCS3D02G469200.
DR Gramene; TraesCS3D03G1033200.1; TraesCS3D03G1033200.1.CDS; TraesCS3D03G1033200.
DR Gramene; TraesPAR_scaffold_048921_01G000100.1; TraesPAR_scaffold_048921_01G000100.1; TraesPAR_scaffold_048921_01G000100.
DR OMA; NIYLSGC; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039203; RGA2/3-like.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR PANTHER; PTHR36766:SF3; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 3.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 16..103
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 175..426
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 31..65
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1553 AA; 174839 MW; 3F1F9B11BD5DD21A CRC64;
MAEVAGMIAS AVGNQVASKL GELVKDEIAL LWGFEDDVEG LREKMEDLQA LLLDADERMR
RGEIQGKAVS LWLAKFKDVA YDVEDVLDDL DATALVEKTQ SKVKLFCCGS DQLLQQSTIA
HSMKTVREKI LKIEMDGQKL NLVPHAAMAE GSRDKETCAA SISGMTTGMV GRDMEKDKII
SLLLTSEANE DISIVPIIGL GGLGKSTLAE SIWADERVNV FDVRIWVHVS EQFDLHKIGS
AIMKHINGSF NLGYCTLQFL HDNLKKELSA TRYLIVLDDL WEEDGNRLEE LKRMLQYGCK
GSRIVVTTRN QSVVEALSSG FLAKEHKMCV VPESDQISLC LLSPGDCWEV MKQRALGPGD
DQSGLQEIGR EIAAKCGGLP IVANALGQIM FERRTVEAWE NIRDTKVDLG LREEHQSKAL
ERLMLSYCYM KLEFKMCFTY LAVFPKGSVM DQHHLIQQWT ALGYIKAHDD GERCINYLLG
MSFIHISRSS SVDPGPMHAK TSQKFTMHDL VHDLASVITS KEFLILDADA TEPRGWNRAR
YCRHARLINY QNQTTVFKDL PITARTIHFR YSGKLQLPKM AFSRSKYIRV LDLSGHSVGR
QSTSSNLDLH GSSVEGQSTS SNVVLPSSIH KSKLLRYLDA TSLPITSLPK SFHTLKHMQT
LILSKCALET LPDTICSLNK LCYLDLSGNV SLTKLPASLG KLSKLSFINL LGCSVLQELP
ESIYELTCLR HLDMSECCTI KKLPDKFGTL LKLIFLNLSG CSKITNLPDN LRLQSLEHMN
LSNCHELENL PKDFGNLQRL RFLSLSDCYK VSLLPESFCQ LIHLKFLDLS DCHELMELPE
CFGHLFELDS LNLTSCCKLQ VLPESFCKLS KLRCLNLSYC MRLDKLPPSF GDLKLQSLDI
SSTESLNALP DSIAEMTSLT RFEAMAGAPD VMARVEEIKK HLIISEEIKH VVQQRENKGC
SSIVELADLT CYELDVQELQ NVKHPEDAER AKLRDKSDLR QLTLHWGTNG GEGKSVLEKL
TPPRTLDYFY LFGYMSKDFP KWMCDISSYL PSLTYLSLCG LGTCDTLPPF GQLPNLRSIC
MAKMPNIRKI GKEFFGQGRP CLKLRSIMLE LMENLTELWT TRSGEENEEF LIPNLHSLCV
SNCPKLKFLP YPPRSMIWYL ENTDEIIAEG GFGKLSSSAL PFDMVINNCS FSPDNWDRLH
HFPTLEVFQV ESCKGLRALP EVIRCFTSLK SLFLKSLKEL ESLPKWLGCF ISLQRLFIKD
CPKIISLPES MKNLTALKVL QLQGCKGWDI LPEWIGLLTS LQKFQIINCP NLTTLPESMK
GLTSLTYLYI KKCQELAVLP QSLGQLITLQ DISIINCPNL TTLPESMKGL TSLTELWIEE
CQGLAMLPEC LGQMISLQKI CIIDCPNLTF LPESMKGLTS LTELWIEECQ GLAMLPECLG
QMISLQKFCI IDCPNLTFLP ESMKKLTALR VLSLKECQRL HMLPEWLQEL TSLEEFNIMD
CPNLISLPQS IQNLPVLKEL YIWGCPILVE RCQGEDAGLI SHIPEVTLHV PEE
//
