ID A0A3B6H611_WHEAT Unreviewed; 248 AA.
AC A0A3B6H611;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Pyridoxal phosphate homeostasis protein {ECO:0000256|HAMAP-Rule:MF_03225};
DE Short=PLP homeostasis protein {ECO:0000256|HAMAP-Rule:MF_03225};
GN ORFNames=CFC21_050098 {ECO:0000313|EMBL:KAF7040177.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS3D02G485100.1};
RN [1] {ECO:0000313|EMBL:KAF7040177.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7040177.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS3D02G485100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS3D02G485100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS3D02G485100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7040177.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7040177.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be
CC involved in intracellular homeostatic regulation of pyridoxal 5'-
CC phosphate (PLP), the active form of vitamin B6. {ECO:0000256|HAMAP-
CC Rule:MF_03225}.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|PIRSR:PIRSR004848-1};
CC -!- SIMILARITY: Belongs to the pyridoxal phosphate-binding protein
CC YggS/PROSC family. {ECO:0000256|HAMAP-Rule:MF_03225,
CC ECO:0000256|RuleBase:RU004514}.
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DR EMBL; CM022219; KAF7040177.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6H611; -.
DR SMR; A0A3B6H611; -.
DR STRING; 4565.A0A3B6H611; -.
DR PaxDb; 4565-Traes_3DL_2AA098CF5-1; -.
DR EnsemblPlants; TraesCS3D02G485100.1; TraesCS3D02G485100.1; TraesCS3D02G485100.
DR Gramene; TraesCLE_scaffold_105663_01G000200.1; TraesCLE_scaffold_105663_01G000200.1; TraesCLE_scaffold_105663_01G000200.
DR Gramene; TraesCS3D02G485100.1; TraesCS3D02G485100.1; TraesCS3D02G485100.
DR Gramene; TraesCS3D03G1078800.1; TraesCS3D03G1078800.1.CDS; TraesCS3D03G1078800.
DR Gramene; TraesPAR_scaffold_032103_01G000200.1; TraesPAR_scaffold_032103_01G000200.1; TraesPAR_scaffold_032103_01G000200.
DR Gramene; TraesRN3D0101128200.1; TraesRN3D0101128200.1; TraesRN3D0101128200.
DR Gramene; TraesROB_scaffold_107835_01G000200.1; TraesROB_scaffold_107835_01G000200.1; TraesROB_scaffold_107835_01G000200.
DR Gramene; TraesWEE_scaffold_103771_01G000100.1; TraesWEE_scaffold_103771_01G000100.1; TraesWEE_scaffold_103771_01G000100.
DR OMA; HIPFHLI; -.
DR OrthoDB; 401867at2759; -.
DR Proteomes; UP000019116; Chromosome 3D.
DR Proteomes; UP000815260; Chromosome 3D.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IBA:GO_Central.
DR CDD; cd06822; PLPDE_III_YBL036c_euk; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR HAMAP; MF_02087; PLP_homeostasis; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR InterPro; IPR011078; PyrdxlP_homeostasis.
DR NCBIfam; TIGR00044; YggS family pyridoxal phosphate-dependent enzyme; 1.
DR PANTHER; PTHR10146; PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN; 1.
DR PANTHER; PTHR10146:SF14; PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PIRSF; PIRSF004848; YBL036c_PLPDEIII; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS01211; UPF0001; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|HAMAP-Rule:MF_03225,
KW ECO:0000256|PIRSR:PIRSR004848-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 37..239
FT /note="Alanine racemase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01168"
FT MOD_RES 45
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03225,
FT ECO:0000256|PIRSR:PIRSR004848-1"
SQ SEQUENCE 248 AA; 26542 MW; D6A5D320A8854C51 CRC64;
MAAAAAEGAA APVAAAMRAV LARAGRAAER SGRAAEAVRV VAIGKTKPVS LLRQLYDAGH
RSFGENYVQE FVTKAPQLPE DIRWHFVGHL QSNKVKSLVA AVPNLDMVEG VGNEKIANHL
DRAVVSLGRE PLKVMVQVNT SGEESKSGID PSKCVELAKH VKLACPNLIL SGLMTIGMKD
YSSTPENFKA LANCKLEVCK ALGIPTEQFE LSMGMSGDFE QAIELGSTNV RVGSTIFGPR
EYPNQKQN
//
