ID A0A3B6HX52_WHEAT Unreviewed; 1166 AA.
AC A0A3B6HX52;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7043022.1, ECO:0000313|EnsemblPlants:TraesCS4A02G167500.1};
GN ORFNames=CFC21_052486 {ECO:0000313|EMBL:KAF7043022.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G167500.1};
RN [1] {ECO:0000313|EMBL:KAF7043022.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7043022.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G167500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G167500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G167500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7043022.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7043022.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022220; KAF7043022.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6HX52; -.
DR STRING; 4565.A0A3B6HX52; -.
DR EnsemblPlants; TraesCS4A02G167500.1; TraesCS4A02G167500.1; TraesCS4A02G167500.
DR Gramene; TraesCAD_scaffold_001425_01G000200.1; TraesCAD_scaffold_001425_01G000200.1; TraesCAD_scaffold_001425_01G000200.
DR Gramene; TraesCLE_scaffold_001178_01G000100.1; TraesCLE_scaffold_001178_01G000100.1; TraesCLE_scaffold_001178_01G000100.
DR Gramene; TraesCS4A02G167500.1; TraesCS4A02G167500.1; TraesCS4A02G167500.
DR Gramene; TraesCS4A03G0454500.1; TraesCS4A03G0454500.1.CDS; TraesCS4A03G0454500.
DR Gramene; TraesPAR_scaffold_009885_01G000100.1; TraesPAR_scaffold_009885_01G000100.1; TraesPAR_scaffold_009885_01G000100.
DR Gramene; TraesROB_scaffold_006194_01G000200.1; TraesROB_scaffold_006194_01G000200.1; TraesROB_scaffold_006194_01G000200.
DR Gramene; TraesWEE_scaffold_003830_01G000100.1; TraesWEE_scaffold_003830_01G000100.1; TraesWEE_scaffold_003830_01G000100.
DR OMA; RETKGHV; -.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000815260; Chromosome 4A.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887:SF497; -; 1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 503..837
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 844..1040
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 98..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 670..697
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 114..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1166 AA; 130092 MW; E7A6F98D852D9CE5 CRC64;
MADEPRDPAL HDPTELVNLK TFECEGNQPE DALDLQNRSK GIRGVEANYA LKLANNPPKR
SKLDEHKVAM LGKKRARQTV IINDEDAKQA GIMTISTPRR QSRAAGEVAA GTQNQLAIRD
QRQSEMMGPE RSNSATPSDR NADSSVDVEL ASPNWSKKMN AEMPPSDGYQ QSVPRQATLR
QSMDSKQFKG RPLSSQRADV TGQNMADQKR ANKRSFVSKK EASANYTQYH DTSVERLLQE
VTSDKFWHNP EESELQSVPG SFESAEEYIR VFEPLLFEEC RAQLHSSYEE SLEAVSRDAH
VMVRIRTVDR RERGWYDVLV LPAHEYKWTF KEGEVAVLSF PRPDSAAQSS DSNRKTVGSN
EDAESECGRL VGRVRRHMPN DTCDPIGAII RFYAGNPSDS SCGINVLGKL QPQSTWYLTG
LGSLATTQRE YIALHAFRRL NVQMQNAILQ PSPEHFPKYQ EQPPAMPDCF TPNFSCHLHH
TFNGPQLSAI HWAAMHTAAG RGNGVVKKQE PWPFTLVQGP PGTGKTHTVW GMLNVIHLVQ
YQHYYAALLK KLAPESYEQV GGSASSTSEA VAAGSMDEVL QSMNQNLFRT LPKLCPKPRM
LVCAPSNAAT DELLARVLDR GFIDGEMRVY RPDVARVGVD SQSRAAQAVS VERRTEQLLM
KGREEVIGWL HQLKVREQQL SQEITLLQRE LNMVAEAGRS QGSFGVDPDM LAQRDRNRDI
LLQKLAASVE SRDKVLVEMS RLLISESRFR VGRNFNLEDA RASLEASFAS EAEIVFTTVS
SSGRKLFSAL NHGFDMVVID EAAQASEVGV LPPLSLGAAR CVLVGDPQQL PATVISKAAG
TLLYSRSLFE RFQQAGCPTI LLSVQYRMHP QIREFPSRYF YQGRLTDSES IANLPDEAFY
KDALMTPYIF YDISHGRESH RGGSSSYQNV HEAQFALCLY EHLQKFLRAN GGKKASVGII
TPYKLQLKCL QREFAEVMNT EEGKDIYINT VDAFQGQERD VIIMSCVRAS NHGVGFVADI
RRMNVALTRA RRALWVIGNA NALMQSEDWA ALVADAKARK CFMDLSSIPS DFLAMNKFSN
ARGLNSSSST RYMRTSGPRP THFDMLPAPR MGMTAGEDGH PNSVARNGSY RNLSNDVGHP
GDRSRDNLQF GRIRGPNPSN DPRRQA
//
