ID A0A3B6I2T2_WHEAT Unreviewed; 1444 AA.
AC A0A3B6I2T2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=CFC21_054078 {ECO:0000313|EMBL:KAF7044918.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G331100.1};
RN [1] {ECO:0000313|EMBL:KAF7044918.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7044918.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G331100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G331100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G331100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7044918.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7044918.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; CM022220; KAF7044918.1; -; Genomic_DNA.
DR SMR; A0A3B6I2T2; -.
DR STRING; 4565.A0A3B6I2T2; -.
DR PaxDb; 4565-Traes_4AL_70CC7A646-1; -.
DR EnsemblPlants; TraesCS4A02G331100.1; TraesCS4A02G331100.1; TraesCS4A02G331100.
DR Gramene; TraesCAD_scaffold_004065_01G000100.1; TraesCAD_scaffold_004065_01G000100.1; TraesCAD_scaffold_004065_01G000100.
DR Gramene; TraesCLE_scaffold_081884_01G000100.1; TraesCLE_scaffold_081884_01G000100.1; TraesCLE_scaffold_081884_01G000100.
DR Gramene; TraesCS4A02G331100.1; TraesCS4A02G331100.1; TraesCS4A02G331100.
DR Gramene; TraesCS4A03G0822400.1; TraesCS4A03G0822400.1.CDS; TraesCS4A03G0822400.
DR Gramene; TraesKAR4A01G0381680.1; cds.TraesKAR4A01G0381680.1; TraesKAR4A01G0381680.
DR Gramene; TraesPAR_scaffold_002860_01G000100.1; TraesPAR_scaffold_002860_01G000100.1; TraesPAR_scaffold_002860_01G000100.
DR Gramene; TraesROB_scaffold_071752_01G000100.1; TraesROB_scaffold_071752_01G000100.1; TraesROB_scaffold_071752_01G000100.
DR Gramene; TraesWEE_scaffold_009727_01G000100.1; TraesWEE_scaffold_009727_01G000100.1; TraesWEE_scaffold_009727_01G000100.
DR OMA; YSKIWVH; -.
DR OrthoDB; 1384804at2759; -.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000815260; Chromosome 4A.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR PANTHER; PTHR48040:SF47; OS02G0318500 PROTEIN; 1.
DR PANTHER; PTHR48040; PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 542..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 578..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..800
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1189..1207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1219..1245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1302..1325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1331..1351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1363..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1413..1436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 169..446
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 843..1096
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1444 AA; 162697 MW; 4B85D971774AA2EF CRC64;
MELTSGSRRS ASAASRRYAG RSLSLHSPSQ AADPFRRAAS QQGRDDDEEN LRWAALEKLP
TYDRMRRAVI PTRPLDVDDA PGLQGADGHE LQAGLVDIDH LASGDAARAL LERVFQDDSE
RFLRRLRERV DRVGIDLPAI EVRYQGLSVE VDAFVGSRAL PTLWNSATNF LQGLVGCLAS
SNKKTINILQ NVNGIIKPSR MTLLLGPPSS GKSTLMRALT GKLDKSLKVS GNITYCGHTF
EEFYPERTSA YVSQYDLHNT EMTVRETLDF SRRCLGVGAR YDMLSELAVR ERQAGIKPDP
EIDAFMKATA VQGQESNIVT DLTLKVLGLD ICADMPIGDD MIRGISGGQK KRVTTGEMLT
GPARALFMDE ISTGLDSSST FQIVKYIGQL VHVMNETVMI SLLQPPPETY NLFDDIILLS
EGYIVYHGPR DNILEFFEAA GFRCPERKGV ADFLQEVTSK KDQQQYWYRD QERYRHVSVL
EFVERFKSFH VGQQMLKELQ IPFDKSKTHP AALTTNKYGQ SSWESFKTVM SREMLLMKRN
SFIYIFKVTQ LLILGIVTMT VFFRTKMPYG QISDSGKYFG ALTFSLIIVL FNGFAELQFT
IKMLPTFYKQ RDFLFFPPWT FGLVNIVSKV PVSLVESAVW VVLTYYVMGF APAAGRFFRQ
LLAFFLTHQM AMGLFRFLGA VLKSMVVANT LGMFVILIIF LFGGFVIPRG DIQPWWIWAY
WSSPMMYSQN AISVNEFLSS RWANPNNDTS IAARTMGEAI LKSRGLFTRD WGFWVSIGAI
VGFAILFNIL YLLALTYLSF GSSSNTVSDK ENENETNTSM PIDEATNRPT RSQITLPFQP
LSLSFNHVNY YVDMPAEMRE QGFAESRLQL LSDISGAFRP GVLTALVGVS GAGKTTLMDV
LAGRKTSGSV EGSITLSGYP KKQETFARIS GYCEQTDIHS PNVTVYESIL YSAWLRLSSD
VDEKTRKIFV EEVMTLVELD VLRNAMVGLP GVDGLSTEQR KRLTIAVELV ANPSIIFMDE
PTSGLDARAA AIVMRAVRNT VNTGRTVVCT IHQPSIDIFE SFDELLLMKR GGRVIYAGEL
GHHSHKIVEY FEAIPGVEKI TEGYNPATWM LEVSSPLAEA HLNINFADIY ANSDLYRKNQ
ELIKELSVAP PGYEDLFFPT KYSQNFYNQC VANFWKQYIS YWKNPAHNAM RFLMTLIYAL
IFGMVFWQKG TKIGSQQDLF NLLGATYAAV FFLGSANCTT VQPVVTIERT VFYREKAAGM
YSPLSYAFAQ TCVEVMYNIM QGIEYTLIIY SMIGYEWKAA KFFYFLFFII SCFNYFTLFG
MMLVALSSSA MLANIIIAFV LPLWNLFAGF LVTRPLIPIW WRWYYWANPV SWTIYGVIGS
QFGDNSSPVS ATGGSPVVVK QFLEDSMGIK HDFLGYVVLA HFAYVIGFFL VFAYSIKMLN
FQKR
//
