ID A0A3B6I504_WHEAT Unreviewed; 620 AA.
AC A0A3B6I504;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN ORFNames=CFC21_054816 {ECO:0000313|EMBL:KAF7045734.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G400600.1};
RN [1] {ECO:0000313|EMBL:KAF7045734.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7045734.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G400600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G400600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G400600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7045734.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7045734.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC ECO:0000256|RuleBase:RU361203}.
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DR EMBL; CM022220; KAF7045734.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6I504; -.
DR SMR; A0A3B6I504; -.
DR STRING; 4565.A0A3B6I504; -.
DR PaxDb; 4565-Traes_4AL_B02A50C63-1; -.
DR EnsemblPlants; TraesCS4A02G400600.1; TraesCS4A02G400600.1; TraesCS4A02G400600.
DR Gramene; TraesCAD_scaffold_018599_01G000600.1; TraesCAD_scaffold_018599_01G000600.1; TraesCAD_scaffold_018599_01G000600.
DR Gramene; TraesCLE_scaffold_027493_01G000100.1; TraesCLE_scaffold_027493_01G000100.1; TraesCLE_scaffold_027493_01G000100.
DR Gramene; TraesCS4A02G400600.1; TraesCS4A02G400600.1; TraesCS4A02G400600.
DR Gramene; TraesCS4A03G0995900.1; TraesCS4A03G0995900.1.CDS; TraesCS4A03G0995900.
DR Gramene; TraesPAR_scaffold_009916_01G000100.1; TraesPAR_scaffold_009916_01G000100.1; TraesPAR_scaffold_009916_01G000100.
DR Gramene; TraesROB_scaffold_008449_01G000600.1; TraesROB_scaffold_008449_01G000600.1; TraesROB_scaffold_008449_01G000600.
DR Gramene; TraesWEE_scaffold_021066_01G000200.1; TraesWEE_scaffold_021066_01G000200.1; TraesWEE_scaffold_021066_01G000200.
DR OMA; GPVQTTW; -.
DR OrthoDB; 456532at2759; -.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000815260; Chromosome 4A.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR040974; Fn3_PAP.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45778:SF46; PURPLE ACID PHOSPHATASE; 1.
DR PANTHER; PTHR45778; PURPLE ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF17808; fn3_PAP; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 22..620
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5040525105"
FT DOMAIN 48..166
FT /note="Purple acid phosphatase Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF17808"
FT DOMAIN 174..284
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 296..511
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 536..594
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 620 AA; 69303 MW; 3A0EB4AE88A2733D CRC64;
MGMAHVVVLA AVLAMATTVS ASPEAGVQPL SKIAIHKATV ELHGSAYVRA SALLLGDGDQ
QEGDTATVTV EYGWQNPATD DWIAVFSPSD FISGSCPNPR RYPTEPLLCT APIKYQYANF
SANYLYWGKG TIQFQLINQR SDFSFALFTG GLENPKLVGL TKLSPFKNPK APVFPRLAQG
KTHDEMAVTW TSGYDVGEAY PFVEWGMVTS GSGGGNPART PAGTLTFNRG SMCGAPARTI
GWRDPGFIHT AFMRGLWPNK EYFYKIGHEL PDGTVVWGKP YTFRAPPTPG QSSLQRVIVF
GDMGKAERDG SNEYANYQPG SLNTTDALVK DLDNFDMVFH IGDLPYANGY ISQWDQFTAQ
VAPISARKPY MIASGNHERD WPNTGGFFDV EDSGGECGVL AETMYYYPAE NRANFWYKVD
YGMFRFCVAD SEHDWREGTP QYKFIKECLS TVDRKHQPWL IFAAHRVLGY SSNKWYAEQG
SFEEPEGRES LQKLWQRYRV DLAFFGHVHN YERTCPLYQN QCVSNERSRY SGTMNGTIFV
VAGGGGSHLN GYTSAIPKWS VFRDRDYGFT KLTAFNHSSL LFEYKRSSDG KVYDNFTIHR
DYRDVLGCVH DSCFPTTLAT
//
