ID A0A3B6I6J3_WHEAT Unreviewed; 582 AA.
AC A0A3B6I6J3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_055403 {ECO:0000313|EMBL:KAF7046373.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4A02G454900.1};
RN [1] {ECO:0000313|EMBL:KAF7046373.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7046373.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4A02G454900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4A02G454900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4A02G454900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7046373.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7046373.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022220; KAF7046373.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6I6J3; -.
DR SMR; A0A3B6I6J3; -.
DR STRING; 4565.A0A3B6I6J3; -.
DR EnsemblPlants; TraesCS4A02G454900.1; TraesCS4A02G454900.1; TraesCS4A02G454900.
DR Gramene; TraesCS4A02G454900.1; TraesCS4A02G454900.1; TraesCS4A02G454900.
DR Gramene; TraesCS4A03G1138600.1; TraesCS4A03G1138600.1.CDS; TraesCS4A03G1138600.
DR Proteomes; UP000019116; Chromosome 4A.
DR Proteomes; UP000815260; Chromosome 4A.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1005; OS07G0197300 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 7..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 186..436
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 582 AA; 65820 MW; 9A80CCF70E4E8D3D CRC64;
MERTAHSLVS NVGQLMANEV WLLRAVGREV VELRDELATM NAVLRMQSEA EDGAVDHFVR
EWMKQVRELA YDADDCIDLY LLRIKRRPSD GFLVRSKRLL VTLFPRRLLA GNIRALRSRA
VTIGERHARY SSSCQALRPS APFAHVPAVW VEPAQALRPA DADDHDQFVG IQEQAKILVA
MMEKEKDDKL QVFSIVGFGG LGKTTLAMEV CRQLETKFDR QAQVSVSQAF DGGNDLRALL
KRVLEQIATV KSRNEKVIME EEEQDSVGNI DRMDVEELTS TLKEQLKGKR YLIVIDDVWT
IAAWATIHSK MPKTTYGSRI IVTTRIDSVG KECSGGSVCK YYSIQRLSLE DSKKLFVRRA
FGPKSTSCPE ELKGSMNNIL KKCNGLPLAI VSIGSLLASY SSPESSHVRE TLCRSIGSQM
ETNPALVGMR NIVTLSFNYL PHELKRCMMY VSIFPEDYQI SEDRLLRRWI AEGLIPEKRG
LTLMETAKAY FNELVNRSMI DQAGCIVTYY NRVDLCRVHD MMLEVMVSKS IEANFISLVG
IQYEGMSYDI VRRLSINDAK QGGGGILHNR ERHNGEWNGE CY
//
