ID A0A3B6IJ40_WHEAT Unreviewed; 1023 AA.
AC A0A3B6IJ40;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN ORFNames=CFC21_056074 {ECO:0000313|EMBL:KAF7047109.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4B02G013300.1};
RN [1] {ECO:0000313|EMBL:KAF7047109.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7047109.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4B02G013300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4B02G013300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4B02G013300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7047109.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7047109.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022221; KAF7047109.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6IJ40; -.
DR STRING; 4565.A0A3B6IJ40; -.
DR EnsemblPlants; TraesCS4B02G013300.1; TraesCS4B02G013300.1; TraesCS4B02G013300.
DR Gramene; TraesCAD_scaffold_188586_01G000100.1; TraesCAD_scaffold_188586_01G000100.1; TraesCAD_scaffold_188586_01G000100.
DR Gramene; TraesCLE_scaffold_020773_01G000300.1; TraesCLE_scaffold_020773_01G000300.1; TraesCLE_scaffold_020773_01G000300.
DR Gramene; TraesCS4B02G013300.1; TraesCS4B02G013300.1; TraesCS4B02G013300.
DR Gramene; TraesCS4B03G0026600.1; TraesCS4B03G0026600.1.CDS; TraesCS4B03G0026600.
DR Gramene; TraesPAR_scaffold_031481_01G000300.1; TraesPAR_scaffold_031481_01G000300.1; TraesPAR_scaffold_031481_01G000300.
DR Gramene; TraesRN4B0100025100.1; TraesRN4B0100025100.1; TraesRN4B0100025100.
DR Gramene; TraesROB_scaffold_155652_01G000100.1; TraesROB_scaffold_155652_01G000100.1; TraesROB_scaffold_155652_01G000100.
DR Gramene; TraesWEE_scaffold_033268_01G000300.1; TraesWEE_scaffold_033268_01G000300.1; TraesWEE_scaffold_033268_01G000300.
DR OMA; DARVWKN; -.
DR OrthoDB; 471309at2759; -.
DR Proteomes; UP000019116; Chromosome 4B.
DR Proteomes; UP000815260; Chromosome 4B.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR33463:SF190; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 251..495
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1023 AA; 115190 MW; 2F0875E7E4924DB8 CRC64;
MLSGTLNVTI KRDSLVRNEL ETRVGLQKLH DCIASACVNF LPSSSGKSSG WSTLLKRIYL
VLEKSRRVVL KSWSAPTSSD QLPPAIRGGQ SHMAHGFQYG VLSPVVGLFV NEIWEPIKKH
FGYCLKPGSK VRKLARAADG LKSHIDTIDE QIQLGKRPRD STKSWIGSAK SIENESVRIK
NEYEERRIYM FGCSWNCLFN YRIGRAAIKK KKEVDELMER PPQNDGIFSL LPPVGKELPL
PPNIVGQNKY MEEIVACIEQ GTTTFIGICG MGGAGKTTLL KQLNNVFSCT AEMHKFDHVI
YVEIDQQPNP ATVQQSIASQ LGLTLGQDES TTARSASLYN FLKERKFLLL VDNLWQPLDL
VKVGIPQGYI QIGPQNRNMV VVTARDRQMC HRMQAHNLVI TLQSLRSDEA WSLFEANAGC
NRLTNSSLQI RGYAEGIVDK CGGLPLALKV VGQAMAMKES EHEWKHAVML LRQSQFHKVP
DAESNLFPIL YISYDHLPDV RTKKCFLFFA LNGTKYYNYS NYLIDLWMGH GLLDEEDDDT
KNCYLRGHSV VGCLKRACLL EEHPRGEIYL RMHDMIRGLA LWIVAEQQGD GCNNKWLLHH
SEEPDEWSKS HRISLSRVSD VKILDYCSCP DLLTLVLDYC WTISKVPVGF FTDAPSLTYL
NLSYTNIQEL PSDVGALVNL RHLDLSYTCI QSIPIESKLL KSLRYLYLGF TAELTYIPDG
IISALGMLRV LDLYYSACLP EHKTHALIKE LESLTRLQFL GFTVADTTSL HRLLDLSKAS
LKSLHIKSVN GLQNLNLCPR IVSKMRAHQL EILAVSGIES LEELLVGGEN DVDSDWLFQS
LDQLQLVDLK KLVGIVRKGV RPRACLPKLR FLLLDGCHSI RSITWVKHLP CLEEVCVIDC
DLISELVTDD DEEVAMSSAM ASFPRLKLLG LSHLTNLKNI CDSTLGVASL QRFLVYNCPM
LTKLPSGLLK EDHAPLILGQ QYWWDQLVWD DGSTKSTLFP FFRELPADFQ GRDSVDVFSA
LVG
//
