ID A0A3B6ITW8_WHEAT Unreviewed; 697 AA.
AC A0A3B6ITW8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4B02G299900.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS4B02G299900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4B02G299900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4B02G299900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
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DR AlphaFoldDB; A0A3B6ITW8; -.
DR SMR; A0A3B6ITW8; -.
DR EnsemblPlants; TraesCS4B02G299900.1; TraesCS4B02G299900.1; TraesCS4B02G299900.
DR Gramene; TraesCAD_scaffold_084126_01G000200.1; TraesCAD_scaffold_084126_01G000200.1; TraesCAD_scaffold_084126_01G000200.
DR Gramene; TraesCLE_scaffold_075630_01G000200.1; TraesCLE_scaffold_075630_01G000200.1; TraesCLE_scaffold_075630_01G000200.
DR Gramene; TraesCS4B02G299900.1; TraesCS4B02G299900.1; TraesCS4B02G299900.
DR Gramene; TraesCS4B03G0788000.1; TraesCS4B03G0788000.1.CDS; TraesCS4B03G0788000.
DR Gramene; TraesPAR_scaffold_059016_01G000300.1; TraesPAR_scaffold_059016_01G000300.1; TraesPAR_scaffold_059016_01G000300.
DR Gramene; TraesRN4B0100818000.1; TraesRN4B0100818000.1; TraesRN4B0100818000.
DR Gramene; TraesROB_scaffold_067387_01G000300.1; TraesROB_scaffold_067387_01G000300.1; TraesROB_scaffold_067387_01G000300.
DR Gramene; TraesWEE_scaffold_097884_01G000200.1; TraesWEE_scaffold_097884_01G000200.1; TraesWEE_scaffold_097884_01G000200.
DR Proteomes; UP000019116; Chromosome 4B.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR48005; LEUCINE RICH REPEAT KINASE 2; 1.
DR PANTHER; PTHR48005:SF14; PROTEIN STRUBBELIG-RECEPTOR FAMILY 7; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..697
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017425552"
FT TRANSMEM 272..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 396..670
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 227..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..250
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..370
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 425
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 697 AA; 75752 MW; CABE8961AD927CD8 CRC64;
MGTRRRGGGM PGAAPLLLLA CCCFCVWPHN QILVAATTDA TDLTALNTLF TSLNSPGQLK
GWQVNGGDPC GESWQGITCS GSSVTAIKLP SLGLSGNLGY NMNTMSSLVE IDMSQNSLGG
GQAIQYNLPT AKLERLNLNH NQLQGKMTDV FSNLGSLTTV DLSFNSLTGD LPEGLSSLSS
VKTLYLQNNQ LTGSINVLAD LPLSDLNVAN NRFTGWIPSQ LKKINSLQTD GNSWTSGPAP
PPPPFTAPPS NRRKSPAKKD SGSSSSDGKS GISGGAVAGI VISLLVVGAI IAFFVIKRKR
KSKREEHFEQ HQPFTSFPSN EVKDMKPYEE STTIDVDSLA SPASVGLKPP AKIERNKSFD
DDDDFSSKPV ARKNNTKPIK AVVYSVADLQ IATDSFSMDN LVGEGTFGRV YRSQFNDGKV
LAVKKLDCTV IPFQSSEDFV ELVSNISILH HPNLNELVGY CMEHGQHLLV YDFHRNGSLH
DLLHLSDEYS KPLSWNSRIK IALGSARALE YLHEVCSPSV VHKNFKSSNI LLDSEYNPHV
SDAGLASFIP DAEFQTAEQS AGCTAPEVDM TGQYTMKSDV YSFGVVMLEL LTGRKPFDSS
KPRSEQSLVR WASPQLHDID ALDRMVDPAL KGLYPAKSLS RFADVLALCV QAEPEFRPPM
SEVVQALVRL VQRANMTKKM LDGDASRRGD DQDQDFI
//
